Literature DB >> 9567757

Effect of ibuprofen and diclofenac sodium on experimental would healing.

S Dvivedi1, S M Tiwari, A Sharma.   

Abstract

Effects of frequently used anti-inflammatory drugs ibuprofen and diclofenac was studied on experimental wound healing in rats. These drugs impede tissue repair by virtue of retarding inflammation. There was 16-36% reduction in wound strength measured in terms of tensile strength in experimental rats. The detrimental effect of anti-inflammatory drugs was confirmed by histological examination of wound and by measuring dry granuloma weight.

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Year:  1997        PMID: 9567757

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  10 in total

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  10 in total

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