Literature DB >> 9566416

Middle cerebral artery main stem thrombosis in two siblings with familial thrombotic thrombocytopenic purpura.

P J Kelly1, C T McDonald, G O Neill, C Thomas, J Niles, G Rordorf.   

Abstract

Idiopathic thrombotic thrombocytopenic purpura (TTP) is frequently complicated by microinfarcts in cerebral cortex and subcortical white matter. We describe two sisters who suffered massive hemispheric infarction due to thrombosis of the middle cerebral artery main stem during exacerbations of TTP. Acute TTP may be associated with intraluminal thrombosis of large-diameter arteries in addition to arterioles and capillaries.

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Year:  1998        PMID： 9566416     DOI： 10.1212/wnl.50.4.1157

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  2 in total

1.  What's new in the diagnosis and pathophysiology of thrombotic thrombocytopenic purpura.

Authors:  J Evan Sadler
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2015

2.  Thrombotic thrombocytopenic purpura with concomitant small- and large-vessel thrombosis, atypical posterior reversible encephalopathy syndrome and cerebral microbleeds.

Authors:  Wong Li Yu; Thomas Leung; Yannie Soo; Jessamyn Lee; Ka Sing Wong
Journal:  Oxf Med Case Reports       Date:  2015-02-03
  2 in total

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