Literature DB >> 9565838

Lithium in the over-65s: who is taking it and who is monitoring it? A survey of older adults on lithium in the Cambridge Mental Health Services catchment area.

L Head1, T Dening.   

Abstract

OBJECTIVES: To determine the prevalence of lithium therapy in the over-65s in the Cambridge Mental Health Services catchment area, to obtain a profile of this group and to find out how well and by whom lithium treatment is being monitored.
METHODS: A census was carried out of patients over the age of 65 in the Cambridge Mental Health Services catchment area who were on lithium therapy on 1 February 1995. The records of these patients were examined retrospectively for demographic details, details of lithium therapy, information about lithium monitoring and risk factors associated with lithium treatment.
RESULTS: One hundred and forty-eight patients were identified representing a point prevalence of 0.27%. GPs carried out lithium monitoring for the majority of this group and 47% had not been seen by a psychiatrist in the 12 months leading up to the census date. Thirty-two per cent of the group were on thyroxine treatment or had raised TSH levels.
CONCLUSIONS: The prevalence of lithium therapy in this study was greater than the prevalences reported in studies of patients of all ages. Standards of monitoring varied widely and were not always better where psychiatrists monitored the treatment, although psychiatrists were more likely than GPs to monitor renal function. There was a high rate of thyroid dysfunction in the study group.

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Year:  1998        PMID: 9565838     DOI: 10.1002/(sici)1099-1166(199803)13:3<164::aid-gps749>3.0.co;2-u

Source DB:  PubMed          Journal:  Int J Geriatr Psychiatry        ISSN: 0885-6230            Impact factor:   3.485


  9 in total

Review 1.  Differential pharmacokinetics of lithium in elderly patients.

Authors:  B A Sproule; B G Hardy; K I Shulman
Journal:  Drugs Aging       Date:  2000-03       Impact factor: 3.923

Review 2.  Lithium dosing and serum concentrations across the age spectrum: from early adulthood to the tenth decade of life.

Authors:  Soham Rej; Serge Beaulieu; Marilyn Segal; Nancy C P Low; Istvan Mucsi; Christina Holcroft; Kenneth Shulman; Karl J Looper
Journal:  Drugs Aging       Date:  2014-12       Impact factor: 3.923

Review 3.  Pathophysiology, diagnosis and management of nephrogenic diabetes insipidus.

Authors:  Detlef Bockenhauer; Daniel G Bichet
Journal:  Nat Rev Nephrol       Date:  2015-06-16       Impact factor: 28.314

Review 4.  Using Lithium in Older Age Bipolar Disorder: Special Considerations.

Authors:  Jocelyn Fotso Soh; Sivan Klil-Drori; Soham Rej
Journal:  Drugs Aging       Date:  2019-02       Impact factor: 3.923

Review 5.  Chronic kidney disease in lithium-treated older adults: a review of epidemiology, mechanisms, and implications for the treatment of late-life mood disorders.

Authors:  Soham Rej; Dominique Elie; Istvan Mucsi; Karl J Looper; Marilyn Segal
Journal:  Drugs Aging       Date:  2015-01       Impact factor: 3.923

Review 6.  A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force.

Authors:  Martha Sajatovic; Sergio A Strejilevich; Ariel G Gildengers; Annemiek Dols; Rayan K Al Jurdi; Brent P Forester; Lars Vedel Kessing; John Beyer; Facundo Manes; Soham Rej; Adriane R Rosa; Sigfried Ntm Schouws; Shang-Ying Tsai; Robert C Young; Kenneth I Shulman
Journal:  Bipolar Disord       Date:  2015-09-19       Impact factor: 6.744

7.  Standards of lithium monitoring in mental health Ttrusts in the UK.

Authors:  Noel Collins; Thomas Re Barnes; Amber Shingleton-Smith; David Gerrett; Carol Paton
Journal:  BMC Psychiatry       Date:  2010-10-12       Impact factor: 3.630

Review 8.  Lithium: updated human knowledge using an evidence-based approach: part III: clinical safety.

Authors:  Etienne Marc Grandjean; Jean-Michel Aubry
Journal:  CNS Drugs       Date:  2009       Impact factor: 5.749

Review 9.  Lithium in late-life mania: a systematic review.

Authors:  Pasquale De Fazio; Raffaele Gaetano; Mariarita Caroleo; Maria Pavia; Giovanbattista De Sarro; Andrea Fagiolini; Cristina Segura-Garcia
Journal:  Neuropsychiatr Dis Treat       Date:  2017-03-09       Impact factor: 2.570

  9 in total

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