| Literature DB >> 9565651 |
P Pohl1, Y N Antonenko, V Y Evtodienko, E E Pohl, S M Saparov, I I Agapov, A G Tonevitsky.
Abstract
The ribosome inactivating plant proteins (RIPs) ricin and viscumin but not Ricinus communis agglutinin are able induce vesicle-vesicle fusion. A model is suggested in which the toxicity of the RIPs is partially determined by their fusogenicity. Herein, fusion is hypothesized to allow the RIPs to leak across endocytic vesicles to approve their access to cytoplasmic ribosomes. Copyright 1998 Elsevier Science B.V.Entities:
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Year: 1998 PMID: 9565651 DOI: 10.1016/s0005-2736(98)00024-8
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002