Literature DB >> 9563249

Detection of benzodiazepine abuse in opiate addicts.

R Browne1, D Sloan, S Fahy, S Keating, C Moran, J O'Connor.   

Abstract

There is an increasing problem with benzodiazepine co-abuse in the opiate dependent population of Dublin. The importance of early detection of this co-abuse is essential as there is an increased risk of dangerous injecting practices such as sharing of needles and criminality in those who co-abuse benzodiazepines and opiates. This study was carried out in the National Drug Treatment Centre, Dublin. It aims to describe the current difficulties in identifying the co-abuse of short acting benzodiazepines including flunitrazepam in a cohort of opiate dependent patients. Using a sample of those attending the clinic it was discovered that standard methods of urinalysis failed to identify 10% of co-abuse. For those patients whose abuse of flunitrazepam is undetected on screening, clinical interventions which aim to minimise the consequence of the co-abuse and reverse the chaotic drug using patterns fail to be put in place at the earliest possible time.

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Year:  1998        PMID: 9563249

Source DB:  PubMed          Journal:  Ir Med J        ISSN: 0332-3102


  3 in total

1.  The detection and quantitation of 7-aminoflunitrazepam, the major urinary metabolite of flunitrazepam, by gas chromatography/mass spectrometry.

Authors:  J Feely; P V Kavanagh; S M McNamara
Journal:  Ir J Med Sci       Date:  1999 Jul-Sep       Impact factor: 1.568

2.  Two types of classification for male opioid dependence: identification of an opioid addict with depressive features.

Authors:  J Modestin; B Matutat; O Würmle
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2005-04-29       Impact factor: 5.270

3.  Benzodiazepine use and misuse among patients in a methadone program.

Authors:  Kevin W Chen; Christine C Berger; Darlene P Forde; Christopher D'Adamo; Eric Weintraub; Devang Gandhi
Journal:  BMC Psychiatry       Date:  2011-05-19       Impact factor: 3.630

  3 in total

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