Correlation among prostate stroma, plasma estrogen levels, and urinary estrogen excretion in patients with benign prostatic hypertrophy.

Plasma testosterone, plasma estradiol, and the total estrogen excretion in the urine were obtained from patients with benign prostatic hypertrophy and correlated to the histological pattern of the resected or enucleated prostates. There was a highly significant increase of prostate stroma in association with higher individual estradiol concentrations and urinary estrogen excretion, while no apparent correlation could be found with testosterone.