Literature DB >> 9562621

Human dis3p, which binds to either GTP- or GDP-Ran, complements Saccharomyces cerevisiae dis3.

T Shiomi1, K Fukushima, N Suzuki, N Nakashima, E Noguchi, T Nishimoto.   

Abstract

Saccharomyces cerevisiae Dis3p, which interacts with Ran/Gsp1p, complements Schizosaccharomyces pombe dis3-54. Consistent with the functional conservation of Dis3p in S. cerevisiae and S. pombe, the human ORF (accession number: R27667) was found to be highly homologous to yeast Dis3p. Based on its nucleotide sequence, we cloned a full-sized human DIS3 cDNA. The cloned human cDNA partly but significantly restored the temperature-sensitivity of S. cerevisiae dis3. Thus, Dis3p was found to be structurally and functionally conserved from yeast to mammals. Consistent with the report that S. cerevisiae Dis3p is identical to Rrp44p, which comprises the exosome involved in ribosomal RNA processing, S. cerevisiae Dis3p was found to be localized in the nucleolus. Similar to S. cerevisiae Dis3p, human Dis3p enhanced RCC1-stimulated nucleotide release from Ran, in a dose-dependent manner, and bound to GTP- or GDP-Ran.

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Year:  1998        PMID： 9562621     DOI： 10.1093/oxfordjournals.jbchem.a022020

Source DB:  PubMed          Journal:  J Biochem        ISSN： 0021-924X            Impact factor:   3.387


  24 in total

1.  Degradation of the unstable EP1 mRNA in Trypanosoma brucei involves initial destruction of the 3'-untranslated region.

Authors:  H Irmer; C Clayton
Journal:  Nucleic Acids Res       Date:  2001-11-15       Impact factor: 16.971

2.  The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Authors:  Rafal Tomecki; Maiken S Kristiansen; Søren Lykke-Andersen; Aleksander Chlebowski; Katja M Larsen; Roman J Szczesny; Karolina Drazkowska; Agnieszka Pastula; Jens S Andersen; Piotr P Stepien; Andrzej Dziembowski; Torben Heick Jensen
Journal:  EMBO J       Date:  2010-06-08       Impact factor: 11.598

3.  Dis3-like 1: a novel exoribonuclease associated with the human exosome.

Authors:  Raymond H J Staals; Alfred W Bronkhorst; Geurt Schilders; Shimyn Slomovic; Gadi Schuster; Albert J R Heck; Reinout Raijmakers; Ger J M Pruijn
Journal:  EMBO J       Date:  2010-06-08       Impact factor: 11.598

4.  Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility.

Authors:  Dewi Astuti; Mark R Morris; Wendy N Cooper; Raymond H J Staals; Naomi C Wake; Graham A Fews; Harmeet Gill; Dean Gentle; Salwati Shuib; Christopher J Ricketts; Trevor Cole; Anthonie J van Essen; Richard A van Lingen; Giovanni Neri; John M Opitz; Patrick Rump; Irene Stolte-Dijkstra; Ferenc Müller; Ger J M Pruijn; Farida Latif; Eamonn R Maher
Journal:  Nat Genet       Date:  2012-02-05       Impact factor: 38.330

5.  Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing.

Authors:  Hong-Wei Wang; Jianjun Wang; Fang Ding; Kevin Callahan; Matthew A Bratkowski; J Scott Butler; Eva Nogales; Ailong Ke
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-17       Impact factor: 11.205

6.  A protein required for nuclear-protein import, Mog1p, directly interacts with GTP-Gsp1p, the Saccharomyces cerevisiae ran homologue.

Authors:  M Oki; T Nishimoto
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-22       Impact factor: 11.205

7.  The Saccharomyces cerevisiae small GTPase, Gsp1p/Ran, is involved in 3' processing of 7S-to-5.8S rRNA and in degradation of the excised 5'-A0 fragment of 35S pre-rRNA, both of which are carried out by the exosome.

Authors:  N Suzuki; E Noguchi; N Nakashima; M Oki; T Ohba; A Tartakoff; M Ohishi; T Nishimoto
Journal:  Genetics       Date:  2001-06       Impact factor: 4.562

8.  Drosophila melanogaster Dis3 N-terminal domains are required for ribonuclease activities, nuclear localization and exosome interactions.

Authors:  Megan Mamolen; Alexandra Smith; Erik D Andrulis
Journal:  Nucleic Acids Res       Date:  2010-04-26       Impact factor: 16.971

9.  A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits.

Authors:  Marlene Oeffinger; Mensur Dlakic; David Tollervey
Journal:  Genes Dev       Date:  2004-01-16       Impact factor: 11.361

10.  The RNA Exosome Channeling and Direct Access Conformations Have Distinct In Vivo Functions.

Authors:  Jaeil Han; Ambro van Hoof
Journal:  Cell Rep       Date:  2016-09-20       Impact factor: 9.423
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