Literature DB >> 9562302

Granule cell dispersion is correlated with early epileptic events in human temporal lobe epilepsy.

D Lurton1, B El Bahh, L Sundstrom, A Rougier.   

Abstract

Granule cell dispersion (GCD) into the dentate gyrus (DG) molecular layer was observed in hippocampal specimens in 10 out of 22 cases of human non-lesional temporal lobe epilepsy (TLE) and was associated with hippocampal sclerosis (HS). The presence of GCD was significantly linked to events of epileptic nature arising during the first 4 years of life but not with the durations of epilepsy, nor the number of seizures. Dispersion could be induced by seizure-linked structural plasticity occurring during a specific early permissive period.

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Year:  1998        PMID: 9562302     DOI: 10.1016/s0022-510x(97)00220-7

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  14 in total

1.  Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus.

Authors:  Christophe Heinrich; Naoki Nitta; Armin Flubacher; Martin Müller; Alexander Fahrner; Matthias Kirsch; Thomas Freiman; Fumio Suzuki; Antoine Depaulis; Michael Frotscher; Carola A Haas
Journal:  J Neurosci       Date:  2006-04-26       Impact factor: 6.167

2.  Neurogenic function in rats with unilateral hippocampal sclerosis that experienced early-life status epilepticus.

Authors:  Mark Dunleavy; Clara K Schindler; Sachiko Shinoda; Shane Crilly; David C Henshall
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2014-12-15

Review 3.  A Mesiotemporal Lobe Epilepsy Mouse Model.

Authors:  Duveau Venceslas; Roucard Corinne
Journal:  Neurochem Res       Date:  2017-03-23       Impact factor: 3.996

4.  Neuropathologic and clinical features of human medial temporal lobe epilepsy.

Authors:  Eun-Kee Bae; Keun-Hwa Jung; Kon Chu; Soon-Tae Lee; Jin-Hee Kim; Kyung-Il Park; Manho Kim; Chun-Ki Chung; Sang Kun Lee; Jae-Kyu Roh
Journal:  J Clin Neurol       Date:  2010-06-30       Impact factor: 3.077

Review 5.  Relevance of seizure-induced neurogenesis in animal models of epilepsy to the etiology of temporal lobe epilepsy.

Authors:  Helen E Scharfman; William P Gray
Journal:  Epilepsia       Date:  2007       Impact factor: 5.864

6.  Physiological and morphological characterization of dentate granule cells in the p35 knock-out mouse hippocampus: evidence for an epileptic circuit.

Authors:  Leena S Patel; H Jürgen Wenzel; Philip A Schwartzkroin
Journal:  J Neurosci       Date:  2004-10-13       Impact factor: 6.167

7.  GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy.

Authors:  Ryuta Koyama; Kentaro Tao; Takuya Sasaki; Junya Ichikawa; Daisuke Miyamoto; Rieko Muramatsu; Norio Matsuki; Yuji Ikegaya
Journal:  Nat Med       Date:  2012-07-15       Impact factor: 53.440

8.  Mapping the spatio-temporal pattern of the mammalian target of rapamycin (mTOR) activation in temporal lobe epilepsy.

Authors:  Long-Ze Sha; Xiao-Liang Xing; Dan Zhang; Yuan Yao; Wan-Chen Dou; Li-Ri Jin; Li-Wen Wu; Qi Xu
Journal:  PLoS One       Date:  2012-06-27       Impact factor: 3.240

Review 9.  Review: Hippocampal sclerosis in epilepsy: a neuropathology review.

Authors:  Maria Thom
Journal:  Neuropathol Appl Neurobiol       Date:  2014-08       Impact factor: 8.090

Review 10.  Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic?

Authors:  G Curia; C Lucchi; J Vinet; F Gualtieri; C Marinelli; A Torsello; L Costantino; G Biagini
Journal:  Curr Med Chem       Date:  2014       Impact factor: 4.530

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