Literature DB >> 9561842

Wnt signaling: why is everything so negative?

J D Brown1, R T Moon.   

Abstract

The Wnt proteins constitute a family of secreted glycoproteins the members of which have essential signaling roles during embryogenesis. The recent identification of several new regulators of this signal transduction pathway have revealed unexpectedly intricate levels of constraint on Wnt-dependent gene activation, and studies in developing embryos and in cell culture systems have allowed a more complete understanding of the functional and biochemical interactions between components of this evolutionarily conserved pathway.

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Year:  1998        PMID： 9561842     DOI： 10.1016/s0955-0674(98)80140-3

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  19 in total

Review 1.  Roles of Wnt proteins in neural development and maintenance.

Authors:  A Patapoutian; L F Reichardt
Journal:  Curr Opin Neurobiol       Date:  2000-06       Impact factor: 6.627

2.  beta-catenin can be transported into the nucleus in a Ran-unassisted manner.

Authors:  F Yokoya; N Imamoto; T Tachibana; Y Yoneda
Journal:  Mol Biol Cell       Date:  1999-04       Impact factor: 4.138

3.  Wound-induced expression and activation of WIG, a novel glycogen synthase kinase 3.

Authors:  C Jonak; D Beisteiner; J Beyerly; H Hirt
Journal:  Plant Cell       Date:  2000-08       Impact factor: 11.277

4.  Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway.

Authors:  H C Wong; J Mao; J T Nguyen; S Srinivas; W Zhang; B Liu; L Li; D Wu; J Zheng
Journal:  Nat Struct Biol       Date:  2000-12

5.  Increased β-catenin/Tcf signaling in pilocytic astrocytomas: a comparative study to distinguish pilocytic astrocytomas from low-grade diffuse astrocytomas.

Authors:  Gangadhara Reddy Sareddy; Khamushavalli Geeviman; Manas Panigrahi; Sundaram Challa; Anita Mahadevan; Phanithi Prakash Babu
Journal:  Neurochem Res       Date:  2011-09-16       Impact factor: 3.996

6.  Simulations of a specific inhibitor of the dishevelled PDZ domain.

Authors:  Xin Chen; Yuefan Deng
Journal:  J Mol Model       Date:  2008-10-25       Impact factor: 1.810

7.  Wnt/beta-catenin/Tcf signaling pathway activation in malignant progression of rat gliomas induced by transplacental N-ethyl-N-nitrosourea exposure.

Authors:  Gangadhara Reddy Sareddy; Sundaram Challa; Manas Panigrahi; Phanithi Prakash Babu
Journal:  Neurochem Res       Date:  2009-01-16       Impact factor: 3.996

8.  No association between polymorphisms of WNT2 and schizophrenia in a Korean population.

Authors:  Hak-Jae Kim; Jin Kyung Park; Su Kang Kim; Sung Wook Kang; Jong Woo Kim; Hyun-Kyung Park; Ah-Rang Cho; Ji Young Song; Joo-Ho Chung
Journal:  BMC Med Genet       Date:  2010-05-24       Impact factor: 2.103

9.  WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors.

Authors:  D Pennica; T A Swanson; J W Welsh; M A Roy; D A Lawrence; J Lee; J Brush; L A Taneyhill; B Deuel; M Lew; C Watanabe; R L Cohen; M F Melhem; G G Finley; P Quirke; A D Goddard; K J Hillan; A L Gurney; D Botstein; A J Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

10.  Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.

Authors:  Patricia Blanco-Arias; Carole A Sargent; Nabeel A Affara
Journal:  Mamm Genome       Date:  2004-01       Impact factor: 2.957
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