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Literature DB >> 9560151

Regulatory factor linked to late-onset diabetes?

S Dutta, S Bonner-Weir, M Montminy, C Wright.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 1998 PMID： 9560151 DOI： 10.1038/33311

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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42 in total

1. Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription.

Authors: M K Thomas; K M Yao; M S Tenser; G G Wong; J F Habener
Journal: Mol Cell Biol Date: 1999-12 Impact factor: 4.272

Review 2. Developmental aspects of the endocrine pancreas.

Authors: Daniel M Kemp; Melissa K Thomas; Joel F Habener
Journal: Rev Endocr Metab Disord Date: 2003-03 Impact factor: 6.514

3. Superior beta cell proliferation, function and gene expression in a subpopulation of rat islets identified by high blood perfusion.

Authors: J Lau; J Svensson; L Grapensparr; Å Johansson; P-O Carlsson
Journal: Diabetologia Date: 2012-02-05 Impact factor: 10.122

4. Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.

Authors: Yoshio Fujitani; Shuko Fujitani; Daniel F Boyer; Maureen Gannon; Yoshiya Kawaguchi; Michael Ray; Masakazu Shiota; Roland W Stein; Mark A Magnuson; Christopher V E Wright
Journal: Genes Dev Date: 2006-01-15 Impact factor: 11.361

5. Missense mutations in the human insulin promoter factor-1 gene are not a common cause of type 2 diabetes mellitus in Taiwan.

Authors: Ming-Yuh Shiau; Chien-Ning Huang; Jung-Hua Liao; Yih-Hsin Chang
Journal: J Endocrinol Invest Date: 2004-12 Impact factor: 4.256

10. pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.

Authors: Maureen Gannon; Elizabeth Tweedie Ables; Laura Crawford; David Lowe; Martin F Offield; Mark A Magnuson; Christopher V E Wright
Journal: Dev Biol Date: 2007-11-04 Impact factor: 3.582

Regulatory factor linked to late-onset diabetes?

1. Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription.

Review 2. Developmental aspects of the endocrine pancreas.

3. Superior beta cell proliferation, function and gene expression in a subpopulation of rat islets identified by high blood perfusion.

4. Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.

5. Missense mutations in the human insulin promoter factor-1 gene are not a common cause of type 2 diabetes mellitus in Taiwan.

6. Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes.

7. Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.

8. Experimental control of pancreatic development and maintenance.

9. Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases.

10. pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.