Literature DB >> 9559814

Effects of slime produced by clinical isolates of coagulase-negative staphylococci on activities of various antimicrobial agents.

M Souli1, H Giamarellou.   

Abstract

A novel in vitro semiquantitative method was developed to investigate the influence of staphylococcal slime on the activities of 22 antimicrobial agents. Pefloxacin, teicoplanin, and vancomycin demonstrated remarkable decreases in efficacy: 30, 52, and 63%, respectively. The activity of rifampin was not significantly reduced (0.99%), whereas all other agents tested were modestly affected (<15% decrease). These data could be influential in the treatment of implant-associated infections caused by slime-producing staphylococci.

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Year:  1998        PMID： 9559814      PMCID： PMC105573          DOI： 10.1128/AAC.42.4.939

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  25 in total

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3.  Coagulase-negative staphylococci isolated from cerebrospinal fluid shunts: importance of slime production, species identification, and shunt removal to clinical outcome.

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Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

6.  Oral rifampin plus ofloxacin for treatment of Staphylococcus-infected orthopedic implants.

Authors:  M Drancourt; A Stein; J N Argenson; A Zannier; G Curvale; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

7.  Staphylococcus epidermidis extracted slime inhibits the antimicrobial action of glycopeptide antibiotics.

Authors:  B F Farber; M H Kaplan; A G Clogston
Journal:  J Infect Dis       Date:  1990-01       Impact factor: 5.226

8.  Inhibition of tobramycin diffusion by binding to alginate.

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9.  Adherence of slime-producing strains of Staphylococcus epidermidis to smooth surfaces.

Authors:  G D Christensen; W A Simpson; A L Bisno; E H Beachey
Journal:  Infect Immun       Date:  1982-07       Impact factor: 3.441

10.  Pseudomonas aeruginosa biofilm as a diffusion barrier to piperacillin.

Authors:  B D Hoyle; J Alcantara; J W Costerton
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191
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6.  In vitro activity of vancomycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci.

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Review 8.  Recent advances in nanotechnology for eradicating bacterial biofilm.

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9.  Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis.

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Review 10.  Microbial Extracellular Polymeric Substances: Ecological Function and Impact on Soil Aggregation.

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