Hepatic adenoma and focal nodular hyperplasia: MR findings with superparamagnetic iron oxide-enhanced MRI.

Two cases are presented in which the MRI findings following superparamagnetic iron oxide (SPIO) enhancement of hepatic adenoma and focal nodular hyperplasia (FNH) are described. Benign liver lesions show uptake of iron oxide particles, which allows differentiation from malignant liver lesions and tumors of other cell origin. There have been several publications in the literature, but the SPIO-enhanced MR findings of hemorrhage in a hepatic adenoma have not been previously described. To illustrate the role of SPIO-enhanced MRI in the differential diagnosis of adenoma from FNH, the SPIO-enhanced MR features of FNH are presented.