Literature DB >> 9557755

Influenza virus-infected epithelial cells present viral antigens to antigen-specific CD8+ cytotoxic T lymphocytes.

H H Nguyen1, P N Boyaka, Z Moldoveanu, M J Novak, H Kiyono, J R McGhee, J Mestecky.   

Abstract

We have investigated the mechanisms involved in the clearance of viral infection at the epithelium level by analyzing the activity of influenza virus-specific cytotoxic T lymphocytes (CTL) against virus-infected CMT-93 intestinal epithelial cells. Epithelial cells infected with live influenza virus effectively present viral antigens and were lysed by both homotypic and heterotypic influenza virus-specific CD8+ T cells. These results shed new light on the control of viral infection through the elimination of virus-infected epithelial cells by virus-specific CTL and demonstrate that CMT-93 cells furnish an appropriate model for in vitro evaluation of CTL activity against virus-infected epithelial cells.

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Year:  1998        PMID： 9557755      PMCID： PMC109702          DOI： 10.1128/JVI.72.5.4534-4536.1998

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  24 in total

1.  Specificity of human cytotoxic T lymphocytes induced by a human papillomavirus type 16 E7-derived peptide.

Authors:  I Jochmus; W Osen; A Altmann; G Buck; B Hofmann; A Schneider; L Gissmann; H G Rammensee
Journal:  J Gen Virol       Date:  1997-07       Impact factor: 3.891

2.  Replication of a waterfowl-origin influenza virus in the kidney and intestine of chickens.

Authors:  R D Slemons; D E Swayne
Journal:  Avian Dis       Date:  1990 Apr-Jun       Impact factor: 1.577

3.  CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity.

Authors:  M J Reddehase; W Mutter; K Münch; H J Bühring; U H Koszinowski
Journal:  J Virol       Date:  1987-10       Impact factor: 5.103

4.  Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus type 16.

Authors:  I Melero; M C Singhal; P McGowan; H S Haugen; J Blake; K E Hellstrom; G Yang; C H Clegg; L Chen
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

5.  Antigen expressed by Salmonella typhimurium is processed for class I major histocompatibility complex presentation by macrophages but not infected epithelial cells.

Authors:  C V Harding; J D Pfeifer
Journal:  Immunology       Date:  1994-12       Impact factor: 7.397

6.  Virus replication in the digestive tract of ducks exposed by aerosol to type-A influenza.

Authors:  R D Slemons; B C Easterday
Journal:  Avian Dis       Date:  1978 Jul-Sep       Impact factor: 1.577

7.  Cellular immune responses of mice to influenza virus vaccines.

Authors:  C S Reiss; J L Schulman
Journal:  J Immunol       Date:  1980-11       Impact factor: 5.422

8.  Clearance of Sendai virus by CD8+ T cells requires direct targeting to virus-infected epithelium.

Authors:  S Hou; P C Doherty
Journal:  Eur J Immunol       Date:  1995-01       Impact factor: 5.532

9.  Induction of Lyt-2+ cytotoxic T lymphocytes following primary and secondary Salmonella infection.

Authors:  M Pope; I Kotlarski; K Doherty
Journal:  Immunology       Date:  1994-02       Impact factor: 7.397

10.  Role of viral infectivity in the induction of influenza virus-specific cytotoxic T cells.

Authors:  T J Braciale; K L Yap
Journal:  J Exp Med       Date:  1978-04-01       Impact factor: 14.307
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  7 in total

1.  The loss of immunodominant epitopes affects interferon-gamma production and lytic activity of the human influenza virus-specific cytotoxic T lymphocyte response in vitro.

Authors:  E G M Berkhoff; M M Geelhoed-Mieras; E J Verschuren; C A van Baalen; R A Gruters; R A M Fouchier; A D M E Osterhaus; G F Rimmelzwaan
Journal:  Clin Exp Immunol       Date:  2007-02-26       Impact factor: 4.330

2.  Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia.

Authors:  Marieke A D van Zoelen; Koenraad F van der Sluijs; Ahmed Achouiti; Sandrine Florquin; Jennie M Braun-Pater; Huan Yang; Peter P Nawroth; Kevin J Tracey; Angelika Bierhaus; Tom van der Poll
Journal:  Virology       Date:  2009-07-09       Impact factor: 3.616

3.  Fish oil-fed mice have impaired resistance to influenza infection.

Authors:  Nicole M J Schwerbrock; Erik A Karlsson; Qing Shi; Patricia A Sheridan; Melinda A Beck
Journal:  J Nutr       Date:  2009-06-23       Impact factor: 4.798

4.  Alpha-C-galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine.

Authors:  Sarah A Kopecky-Bromberg; Kathryn A Fraser; Natalie Pica; Elena Carnero; Thomas M Moran; Richard W Franck; Moriya Tsuji; Peter Palese
Journal:  Vaccine       Date:  2009-04-23       Impact factor: 3.641

5.  CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation.

Authors:  A Suzuki; T Hanada; K Mitsuyama; T Yoshida; S Kamizono; T Hoshino; M Kubo; A Yamashita; M Okabe; K Takeda; S Akira; S Matsumoto; A Toyonaga; M Sata; A Yoshimura
Journal:  J Exp Med       Date:  2001-02-19       Impact factor: 14.307

6.  Immunity to Respiratory Infection Is Reinforced Through Early Proliferation of Lymphoid TRM Cells and Prompt Arrival of Effector CD8 T Cells in the Lungs.

Authors:  Jenny E Suarez-Ramirez; Karthik Chandiran; Stefan Brocke; Linda S Cauley
Journal:  Front Immunol       Date:  2019-06-14       Impact factor: 7.561

Review 7.  Respiratory Barrier as a Safeguard and Regulator of Defense Against Influenza A Virus and Streptococcus pneumoniae.

Authors:  Kim S LeMessurier; Meenakshi Tiwary; Nicholas P Morin; Amali E Samarasinghe
Journal:  Front Immunol       Date:  2020-02-04       Impact factor: 7.561
  7 in total

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