Literature DB >> 9557731

Cryoelectron microscopic examination of human immunodeficiency virus type 1 virions with mutations in the cyclophilin A binding loop.

L B Kong1, D An, B Ackerson, J Canon, O Rey, I S Chen, P Krogstad, P L Stewart.   

Abstract

The human immunodeficiency virus type 1 capsid protein contains a conserved P217X4PX2PX5P231 motif. Mutation at Pro-222 decreases virion incorporation of cyclophilin A, while mutation at Pro-231 abolishes infectivity. Although viral RNA incorporation and protease cleavage of the Gag precursor were not affected by these mutations, cryoelectron microscopy revealed a loss of virion maturation in P231A particles.

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Year:  1998        PMID： 9557731      PMCID： PMC109671          DOI： 10.1128/JVI.72.5.4403-4407.1998

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  44 in total

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Authors:  A K Shah; P L Stewart
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2.  Economical apparatus for safe, accurate recovery of biohazardous or radioactive gradient fractions.

Authors:  J Canon; P Krogstad
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3.  HIV-1 Gag protein associates with F-actin present in microfilaments.

Authors:  O Rey; J Canon; P Krogstad
Journal:  Virology       Date:  1996-06-15       Impact factor: 3.616

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Authors:  M V Nermut; C Grief; S Hashmi; D J Hockley
Journal:  AIDS Res Hum Retroviruses       Date:  1993-10       Impact factor: 2.205

5.  Functional association of cyclophilin A with HIV-1 virions.

Authors:  M Thali; A Bukovsky; E Kondo; B Rosenwirth; C T Walsh; J Sodroski; H G Göttlinger
Journal:  Nature       Date:  1994-11-24       Impact factor: 49.962

6.  Structure of the amino-terminal core domain of the HIV-1 capsid protein.

Authors:  R K Gitti; B M Lee; J Walker; M F Summers; S Yoo; W I Sundquist
Journal:  Science       Date:  1996-07-12       Impact factor: 47.728

7.  Specific incorporation of cyclophilin A into HIV-1 virions.

Authors:  E K Franke; H E Yuan; J Luban
Journal:  Nature       Date:  1994-11-24       Impact factor: 49.962

8.  Vpr-induced cell cycle arrest is conserved among primate lentiviruses.

Authors:  V Planelles; J B Jowett; Q X Li; Y Xie; B Hahn; I S Chen
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103

9.  Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription.

Authors:  D Braaten; E K Franke; J Luban
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

10.  Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity.

Authors:  A S Reicin; S Paik; R D Berkowitz; J Luban; I Lowy; S P Goff
Journal:  J Virol       Date:  1995-02       Impact factor: 5.103
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  11 in total

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Authors:  Uta K von Schwedler; Kirsten M Stray; Jennifer E Garrus; Wesley I Sundquist
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

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Authors:  Jeremy Luban
Journal:  J Virol       Date:  2006-09-06       Impact factor: 5.103

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Authors:  Ian B Hogue; Jonathan R Grover; Ferri Soheilian; Kunio Nagashima; Akira Ono
Journal:  J Virol       Date:  2011-08-03       Impact factor: 5.103

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Authors:  Elena Sokolskaja; Silvia Olivari; Madeleine Zufferey; Caterina Strambio-De-Castillia; Massimo Pizzato; Jeremy Luban
Journal:  J Virol       Date:  2010-02-24       Impact factor: 5.103

5.  Identification of 2-(4-N,N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo.

Authors:  Guzmán Alvarez; Lisa van Pul; Xavier Robert; Zoraima Artía; Ad C van Nuenen; Mathieu Long; Natalia Sierra; Williams Porcal; Neeltje A Kootstra; Christophe Guillon
Journal:  BMC Pharmacol Toxicol       Date:  2022-06-28       Impact factor: 2.605

6.  HIV-1 Gag associates with specific uropod-directed microdomains in a manner dependent on its MA highly basic region.

Authors:  G Nicholas Llewellyn; Jonathan R Grover; Balaji Olety; Akira Ono
Journal:  J Virol       Date:  2013-03-27       Impact factor: 5.103

7.  Roles played by capsid-dependent induction of membrane curvature and Gag-ESCRT interactions in tetherin recruitment to HIV-1 assembly sites.

Authors:  Jonathan R Grover; G Nicholas Llewellyn; Ferri Soheilian; Kunio Nagashima; Sarah L Veatch; Akira Ono
Journal:  J Virol       Date:  2013-02-13       Impact factor: 5.103

8.  Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivity.

Authors:  Elena Sokolskaja; David M Sayah; Jeremy Luban
Journal:  J Virol       Date:  2004-12       Impact factor: 5.103

9.  Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity.

Authors:  Samir Abdurahman; Stefan Höglund; Anders Höglund; Anders Vahlne
Journal:  Retrovirology       Date:  2007-03-19       Impact factor: 4.602

10.  Single-molecule imaging of HIV-1 envelope glycoprotein dynamics and Gag lattice association exposes determinants responsible for virus incorporation.

Authors:  Nairi Pezeshkian; Nicholas S Groves; Schuyler B van Engelenburg
Journal:  Proc Natl Acad Sci U S A       Date:  2019-11-22       Impact factor: 11.205
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