| Literature DB >> 9556225 |
R Wiśnicka1, A Krzepiłko, J Wawryn, Z Krawiec, T Biliński.
Abstract
It has been found that yeast mutants deficient in cytosolic superoxide dismutase CuZnSOD are hypersensitive to ferrous iron. In contrast mutants that are deficient in catalases and cytochrome c peroxidase do not differ from the standard strain in this respect. These findings suggest that iron toxicity may depend on the redox status of the cell. They also shed light on the role of superoxide dismutases in preventing the toxic effects of oxygen.Entities:
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Year: 1998 PMID： 9556225 DOI： 10.1080/15216549800201672
Source DB: PubMed Journal: Biochem Mol Biol Int ISSN： 1039-9712