| Literature DB >> 9554250 |
M A Renier1, A Vereecken, E Van Herck, D Straetmans, P Ramaekers, J Vanderheyden, H Degezelle, P Buytaert.
Abstract
Levels of inhibin A and B as well as other hormones in serum samples obtained during the pill-free interval in women taking combined oral contraceptives (OC) were measured to asses the extent of ovarian activity during that period. Type of pill and day of pill-free interval were recorded during routine gynecologic check-ups, if patients were in the pill-free period and had taken their pills regularly in the previous cycle. In addition to inhibin A and B, serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), and progesterone were also quantified. Inhibin B levels rise significantly in parallel with rising levels of FSH, LH, and E2. Progesterone levels were completely suppressed and inhibin A levels rose slightly but insignificantly. Inhibins are sensitive biochemical markers of ovarian activity in pill-free intervals.Entities:
Keywords: Belgium; Biology; Clinical Research; Contraception; Contraceptive Methods--pharmacodynamics; Developed Countries; Endocrine System; Europe; Family Planning; Genitalia; Genitalia, Female; Hormones; Oral Contraceptives, Combined--pharmacodynamics; Oral Contraceptives--pharmacodynamics; Ovarian Effects; Ovary; Physiology; Pituitary Hormones; Research Methodology; Research Report; Urogenital System; Western Europe
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Year: 1998 PMID： 9554250 DOI： 10.1016/s0010-7824(97)00206-0
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375