| Literature DB >> 9551786 |
M J Koepp1, M L Hansen, R M Pressler, D J Brooks, U Brandl, B Guldin, J S Duncan, S Ried.
Abstract
The pathophysiological and neuroanatomical bases of reading epilepsy (RE) are unclear. We performed video-EEG, high quality MRI and [11C]diprenorphine PET in a patient with RE to detect structural and functional abnormalities. EEG showed multifocal seizure onset bilaterally in temporal and fronto-central regions. MRI was normal, whereas [11C]diprenorphine PET revealed peri-ictal opioid binding decreases in both temporal lobes and the left frontal lobe. These findings confirm that RE is due to abnormal activity in the network subserving reading.Entities:
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Year: 1998 PMID： 9551786 DOI： 10.1016/s0920-1211(97)00056-9
Source DB: PubMed Journal: Epilepsy Res ISSN： 0920-1211 Impact factor: 3.045