Literature DB >> 9549882

Naphthoquinone esters from the root of Rhinacanthus nasutus.

T S Wu1, H C Hsu, P L Wu, Y L Leu, Y Y Chan, C Y Chern, M Y Yeh, H J Tien.   

Abstract

Reinvestigation of the root of Rhinacanthus nasutus afforded, in addition to rhinacanthin-A to -D reported previously, two new dimethyldihydropyranonaphthoquinone esters (5, 6) and eight new 2-hydroxy-1,4-naphthoquinone esters (7-14) were isolated. The stereochemistry of rhinacanthin-A was determined as the R configuration. Compounds rhinacanthin-G to -N, belong to a class of 2-hydroxy-3-(3-hydroxy-2,2-dimethylpropyl)-1,4-naphthoquinone esters, and so far have been isolated only in this plant. Their biosynthesis is also discussed.

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Year:  1998        PMID： 9549882     DOI： 10.1248/cpb.46.413

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  6 in total

1.  Synergy between rhinacanthins from Rhinacanthus nasutus in inhibition against mosquito cytochrome P450 enzymes.

Authors:  Rattanawadee Kotewong; Phisit Pouyfung; Panida Duangkaew; Aruna Prasopthum; Pornpimol Rongnoparut
Journal:  Parasitol Res       Date:  2015-04-15       Impact factor: 2.289

2.  Rhinacanthin C Alleviates Amyloid-β Fibrils' Toxicity on Neurons and Attenuates Neuroinflammation Triggered by LPS, Amyloid-β, and Interferon-γ in Glial Cells.

Authors:  Kai-An Chuang; Ming-Han Li; Ni-Hsuan Lin; Chih-Hsuan Chang; I-Huang Lu; I-Hong Pan; Tomoya Takahashi; Ming-Der Perng; Shu-Fang Wen
Journal:  Oxid Med Cell Longev       Date:  2017-10-18       Impact factor: 6.543

3.  Antileishmanial Activity of Handroanthus serratifolius (Vahl) S. Grose (Bignoniaceae).

Authors:  Erica Vanessa Souza Costa; Heliton Patrick Cordovil Brígido; João Victor da Silva E Silva; Marlia Regina Coelho-Ferreira; Geraldo Célio Brandão; Maria Fâni Dolabela
Journal:  Evid Based Complement Alternat Med       Date:  2017-02-12       Impact factor: 2.629

4.  Rhinacanthins-rich Extract Enhances Glucose Uptake and Inhibits Adipogenesis in 3T3-L1 Adipocytes and L6 Myotubes.

Authors:  Muhammad Ajmal Shah; Chanawee Jakkawanpitak; Decha Sermwittayawong; Pharkphoom Panichayupakaranant
Journal:  Pharmacogn Mag       Date:  2018-01-31       Impact factor: 1.085

5.  Rhinacanthus nasutus protects cultured neuronal cells against hypoxia induced cell death.

Authors:  James M Brimson; Tewin Tencomnao
Journal:  Molecules       Date:  2011-07-26       Impact factor: 4.411

6.  Superoxide Scavenging and Antiglycation Activity of Rhinacanthins-rich Extract Obtained from the Leaves of Rhinacanthus nasutus.

Authors:  Muhammad Ajmal Shah; Haji Muhammad; Yasir Mehmood; Ruqaiya Khalil; Zaheer Ul-Haq; Pharkphoom Panichayupakaranant
Journal:  Pharmacogn Mag       Date:  2017-11-13       Impact factor: 1.085
  6 in total

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