Literature DB >> 954979

The electrophysiological effects of ionophore X-537A on cardiac purkinje fibres.

J M Gelles.   

Abstract

Using classical microelectrode techniques in canine cardiac Purkinje fibres, calcium ionophore X-537A was shown to shorten the action potential, hyperpolarizing the membrane and lowering the plateau, suggesting that intracellular calcium controls membrane permeability to potassium in this preparation.

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Year:  1976        PMID： 954979     DOI： 10.1007/BF02003760

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  Effect of transmembrane potential on the manifestations of ouabain toxicity in sheep cardiac Purkinje fibres.

Authors:  J M Gelles; R S Aronson; B F Hoffman
Journal:  Cardiovasc Res       Date:  1975-09       Impact factor: 10.787

2.  Activation of a voltage-insensitive conductance by inward calcium current.

Authors:  W Clusin; D C Spray; M V Bennett
Journal:  Nature       Date:  1975-07-31       Impact factor: 49.962

3.  Effects of an inotropic agent, RO 2-2985 (X-537A), on regional blood flow and myocardial function in chronically instrumented conscious dogs and anesthetized dogs.

Authors:  H G Hanley; R M Lewis; C J Hartley; D Franklin; A Schwartz
Journal:  Circ Res       Date:  1975-08       Impact factor: 17.367

4.  Is potassium conductance of cardiac Purkinje fibres controlled by (Ca2+)?

Authors:  G Isnberg
Journal:  Nature       Date:  1975-01-24       Impact factor: 49.962

5.  The effect of substances releasing intracellular calcium ions on sodium-dependent calcium efflux from guinea-pig auricles.

Authors:  H Jundt; H Porzig; H Reuter; J W Stucki
Journal:  J Physiol       Date:  1975-03       Impact factor: 5.182

6.  Properties of ionophores with broad range cation selectivity.

Authors:  B C Pressman
Journal:  Fed Proc       Date:  1973-06

7.  A new method for producing short cardiac Purkinje fibers suitable for voltage clamp.

Authors:  R S Aronson; J M Gelles; B F Hoffman
Journal:  J Appl Physiol       Date:  1973-04       Impact factor: 3.531

8.  The sensitivity of Helix aspersa neurones to injected calcium ions.

Authors:  R W Meech
Journal:  J Physiol       Date:  1974-03       Impact factor: 5.182
  8 in total
  1 in total

1.  Electrogenic hyperpolarization in canine cardiac Purkinje fibres exposed to calcium ionophores.

Authors:  J M Gelles; R Zeiler
Journal:  Experientia       Date:  1978-05-15
  1 in total

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