Literature DB >> 954976

On the mechanism of pyrogenic action of ricin.

G A Balint.   

Abstract

The incubation of rabbit white blood cells with ricin, the toxic protein of castor oil seeds, leads to the production of endogenous pyrogens. This induction can be inhibited by the antibiotics actinomycin D or cycloheximide. The results are discussed in terms of disturbed corticosteroid- and Mg2+-levels.

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Year:  1976        PMID： 954976     DOI： 10.1007/BF02003754

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  16 in total

1.  Selected aspects of steroid pharmacology.

Authors:  A KAPPAS; R H PALMER
Journal:  Pharmacol Rev       Date:  1963-03       Impact factor: 25.468

2.  Pathogenesis of fever.

Authors:  E ATKINS
Journal:  Physiol Rev       Date:  1960-07       Impact factor: 37.312

3.  Body temperature: possible ionic mechanism in the hypothalamus controlling the set point.

Authors:  R D Myers; W L Veale
Journal:  Science       Date:  1970-10-02       Impact factor: 47.728

4.  Polyribosome disaggregation in rat liver following administration of the phytotoxic proteins, abrin and ricin.

Authors:  J Y Lin; C C Pao; S T Ju; T C Tung
Journal:  Cancer Res       Date:  1972-05       Impact factor: 12.701

5.  Mechanism of action of pyrogen.

Authors:  W Feldberg; P N Saxena
Journal:  J Physiol       Date:  1970-11       Impact factor: 5.182

6.  Studies on the pathogenesis of fever. 18. Activation of leukocytes for pyrogen production.

Authors:  D M Moore; S F Cheuk; J D Morton; R D Berlin; W B Wood
Journal:  J Exp Med       Date:  1970-01-01       Impact factor: 14.307

7.  Studies on the antipyretic action of cortisone in pyrogen-induced fever.

Authors:  E ATKINS; F ALLISON; M R SMITH; W B WOOD
Journal:  J Exp Med       Date:  1955-04-01       Impact factor: 14.307

8.  Studies on the pathogenesis of fever. I. The effect of injection of extracts and suspensions of uninfected rabbit tissues upon the body temperature of normal rabbits.

Authors:  I L BENNETT; P B BEESON
Journal:  J Exp Med       Date:  1953-11       Impact factor: 14.307

9.  THE PRESENCE OF ENDOGENOUS PYROGEN IN NORMAL RABBIT TISSUES.

Authors:  E S SNELL; E ATKINS
Journal:  J Exp Med       Date:  1965-06-01       Impact factor: 14.307

10.  Studies on the origin of human leukocytic pyrogen.

Authors:  J J Nordlund; R K Root; S M Wolff
Journal:  J Exp Med       Date:  1970-04-01       Impact factor: 14.307
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  1 in total

1.  The effect of ricin on the mixed function microsomal oxidase system in the rat liver.

Authors:  G A Balint
Journal:  Naturwissenschaften       Date:  1990-12
  1 in total

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