Literature DB >> 954961

The effects of various agents in vitro on homocarnosine-carnosine synthetase from rat brain.

R H Ng, F D Marshall.   

Abstract

The present paper reports the first evidence that homocarnosine-carnosine synthetase from rat brain requires free sulfhydryl groups for activity. The activity of the synthetase can be stabilized by dithioerythritol and inhibited strongly by Cu2+, Cd2+, Hg2+, Zn2+, and to a lesser extent by Ca2+, Ni2+, Li, chlorpromazine, alpha-methyl DOPA and norepinephrine at the concentrations tested.

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Year:  1976        PMID： 954961     DOI： 10.1007/BF02003717

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  The distribution of homocarnosine in mammals.

Authors:  D ABRAHAM; J J PISANO; S UDENFRIEND
Journal:  Arch Biochem Biophys       Date:  1962-11       Impact factor: 4.013

2.  The effects of promazines on mitochondrial adenosine triphosphatase reactions.

Authors:  H LOW
Journal:  Biochim Biophys Acta       Date:  1959-03

3.  Some properties of a homocarnosine-carnosine synthetase isolated from rat brain.

Authors:  S D Skaper; S Das; F D Marshall
Journal:  J Neurochem       Date:  1973-12       Impact factor: 5.372

4.  Huntington's chorea. Deficiency of gamma-aminobutyric acid in brain.

Authors:  T L Perry; S Hansen; M Kloster
Journal:  N Engl J Med       Date:  1973-02-15       Impact factor: 91.245

5.  The effect of various agents in the levels of homocarnosine in rat brain.

Authors:  F D Marshall; W C Yockey
Journal:  Biochem Pharmacol       Date:  1968-04       Impact factor: 5.858

6.  Partial reactions catalyzed by -glutamylcysteine synthetase and evidence for an activated glutamate intermediate.

Authors:  M Orlowski; A Meister
Journal:  J Biol Chem       Date:  1971-12-10       Impact factor: 5.157

7.  Carnosine in the primary olfactory pathway.

Authors:  F L Margolis
Journal:  Science       Date:  1974-05-24       Impact factor: 47.728

8.  The effect of reserpine, chlorpromazine and neumbutal on levels of dipeptides in rat brain and muscle.

Authors:  F D Marshall
Journal:  Life Sci       Date:  1973-07-16       Impact factor: 5.037

9.  Regional distribution of homocarnosine and other ninhydrin-positive substances in brains of malnourished monkeys.

Authors:  C O Enwonwu; B S Worthington
Journal:  J Neurochem       Date:  1974-06       Impact factor: 5.372

10.  Properties of brain L-glutamate decarboxylase: inhibition studies.

Authors:  J Y Wu; E Roberts
Journal:  J Neurochem       Date:  1974-10       Impact factor: 5.372
  10 in total

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