Literature DB >> 9547884

The role of phosphodiesterase enzymes in allergy and asthma.

D Spina1, L J Landells, C P Page.   

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Year:  1998        PMID： 9547884     DOI： 10.1016/s1054-3589(08)60125-8

Source DB:  PubMed          Journal:  Adv Pharmacol        ISSN： 1054-3589


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  7 in total

1.  Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1).

Authors:  Simon J MacKenzie; George S Baillie; Ian McPhee; Carolynn MacKenzie; Rachael Seamons; Theresa McSorley; Jenni Millen; Matthew B Beard; Gino van Heeke; Miles D Houslay
Journal:  Br J Pharmacol       Date:  2002-06       Impact factor: 8.739

2.  Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases.

Authors:  G S Baillie; S J MacKenzie; I McPhee; M D Houslay
Journal:  Br J Pharmacol       Date:  2000-10       Impact factor: 8.739

Review 3.  PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.

Authors:  Miles D Houslay; David R Adams
Journal:  Biochem J       Date:  2003-02-15       Impact factor: 3.857

4.  Pharmacokinetic and pharmacodynamic profile following oral administration of the phosphodiesterase (PDE)4 inhibitor V11294A in healthy volunteers.

Authors:  Donna Donigi Gale; Linda J Landells; Domenico Spina; Alan J Miller; Kate Smith; Terry Nichols; Yakov Rotshteyn; Alfred Tonelli; Peter Lacouture; Ronald M Burch; Clive P Page; Brian J O'Connor
Journal:  Br J Clin Pharmacol       Date:  2002-11       Impact factor: 4.335

Review 5.  Phosphodiesterase-4 inhibitors in the treatment of inflammatory lung disease.

Authors:  Domenico Spina
Journal:  Drugs       Date:  2003       Impact factor: 9.546

6.  Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte-macrophage differentiation of human U937 cells.

Authors:  Malcolm C Shepherd; George S Baillie; David I Stirling; Miles D Houslay
Journal:  Br J Pharmacol       Date:  2004-04-05       Impact factor: 8.739

7.  The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma.

Authors:  Brian R Leaker; Dave Singh; Ferhana Y Ali; Peter J Barnes; Brian O'Connor
Journal:  BMC Pulm Med       Date:  2014-10-28       Impact factor: 3.317
  7 in total

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