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Literature DB >> 9545415

Replicative senescence in the immune system: impact of the Hayflick limit on T-cell function in the elderly.

R B Effros¹.

Abstract

Mesh：

Year: 1998 PMID： 9545415 PMCID： PMC1377102 DOI： 10.1086/301845

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

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26 in total

1. THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS.

Authors: L HAYFLICK
Journal: Exp Cell Res Date: 1965-03 Impact factor: 3.905

2. Extension of life-span by introduction of telomerase into normal human cells.

Authors: A G Bodnar; M Ouellette; M Frolkis; S E Holt; C P Chiu; G B Morin; C B Harley; J W Shay; S Lichtsteiner; W E Wright
Journal: Science Date: 1998-01-16 Impact factor: 47.728

3. Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence.

Authors: R B Effros; N Boucher; V Porter; X Zhu; C Spaulding; R L Walford; M Kronenberg; D Cohen; F Schächter
Journal: Exp Gerontol Date: 1994 Nov-Dec Impact factor: 4.032

Review 4. Lifespans of T lymphocytes.

Authors: M Adibzadeh; E Mariani; C Bartoloni; I Beckman; G Ligthart; E Remarque; S Shall; R Solana; G M Taylor; Y Barnett; G Pawelec
Journal: Mech Ageing Dev Date: 1996-10-25 Impact factor: 5.432

5. Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells.

Authors: B L Levine; W B Bernstein; M Connors; N Craighead; T Lindsten; C B Thompson; C H June
Journal: J Immunol Date: 1997-12-15 Impact factor: 5.422

Review 6. Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?

Authors: R B Effros; G Pawelec
Journal: Immunol Today Date: 1997-09

7. Mechanism of telomerase induction during T cell activation.

Authors: A G Bodnar; N W Kim; R B Effros; C P Chiu
Journal: Exp Cell Res Date: 1996-10-10 Impact factor: 3.905

8. Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis.

Authors: R B Effros; R Allsopp; C P Chiu; M A Hausner; K Hirji; L Wang; C B Harley; B Villeponteau; M D West; J V Giorgi
Journal: AIDS Date: 1996-07 Impact factor: 4.177

9. Characterization of cloned murine cytolytic T cell lines.

Authors: H D Engers; D Collavo; M North; H von Boehmer; W Haas; H Hengartner; M Nabholz
Journal: J Immunol Date: 1980-10 Impact factor: 5.422

10. Regulated expression of telomerase activity in human T lymphocyte development and activation.

Authors: N P Weng; B L Levine; C H June; R J Hodes
Journal: J Exp Med Date: 1996-06-01 Impact factor: 14.307

19 in total

1. Brain Aging and Regeneration after Injuries: an Organismal approach.

Authors: Ana-Maria Buga; Raluca Vintilescu; Oltin Tiberiu Pop; Aurel Popa-Wagner
Journal: Aging Dis Date: 2011-09-20 Impact factor: 6.745

2. Role of CD8 T Cell Replicative Senescence in Human Aging and in HIV-mediated Immunosenescence.

Authors: Jeffrey N Dock; Rita B Effros
Journal: Aging Dis Date: 2011-10 Impact factor: 6.745

3. Homeostasis of the naive CD4+ T cell compartment during aging.

Authors: Ryan D Kilpatrick; Tammy Rickabaugh; Lance E Hultin; Patricia Hultin; Mary Ann Hausner; Roger Detels; John Phair; Beth D Jamieson
Journal: J Immunol Date: 2008-02-01 Impact factor: 5.422

Review 4. A synopsis on aging-Theories, mechanisms and future prospects.

Authors: João Pinto da Costa; Rui Vitorino; Gustavo M Silva; Christine Vogel; Armando C Duarte; Teresa Rocha-Santos
Journal: Ageing Res Rev Date: 2016-06-25 Impact factor: 10.895

Review 5. T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment.

Authors: Joel Crespo; Haoyu Sun; Theodore H Welling; Zhigang Tian; Weiping Zou
Journal: Curr Opin Immunol Date: 2013-01-06 Impact factor: 7.486

6. Methods for Characterization of Senescent Circulating and Tumor-Infiltrating T-Cells: An Overview from Multicolor Flow Cytometry to Single-Cell RNA Sequencing.

Authors: Rossana Franzin; Alessandra Stasi; Giuseppe Castellano; Loreto Gesualdo
Journal: Methods Mol Biol Date: 2021

7. Telomere length measurement and determination of immunosenescence-related markers (CD28, CD45RO, CD45RA, interferon-gamma and interleukin-4) in skin-homing T cells expressing the cutaneous lymphocyte antigen: indication of a non-ageing T-cell subset.

Authors: Karsten Neuber; Saskia Schmidt; Andrea Mensch
Journal: Immunology Date: 2003-05 Impact factor: 7.397