Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Translation control: connecting mitogens and the ribosome.

Literature DB >> 9545190

Translation control: connecting mitogens and the ribosome.

Abstract

The identification of 3-phosphoinositide-dependent kinase 1 (PDK1) as one of the elusive 70 kDa S6 kinase kinases has filled a gap in the signaling pathway by which extracellular receptors regulate translation. Will it cause us to reconsider the relationships between previously identified members of the pathway?

Entities: Gene

Mesh：

Substances：

Year: 1998 PMID： 9545190 DOI： 10.1016/s0960-9822(98)70152-6

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

Keyword Cloud
Cited

61 in total

1. Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.

Authors: A Khan; A M Pepio; W S Sossin
Journal: J Neurosci Date: 2001-01-15 Impact factor: 6.167

2. Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker rat.

Authors: Anjaiah Katta; Sudarsanam Kundla; Sunil K Kakarla; Miaozong Wu; Jacqueline Fannin; Satyanarayana Paturi; Hua Liu; Hari S Addagarla; Eric R Blough
Journal: Am J Physiol Regul Integr Comp Physiol Date: 2010-10-06 Impact factor: 3.619

Review 3. Cell cycle control mechanisms in B-1 and B-2 lymphoid subsets.

Authors: Michael J Piatelli; Debra Tanguay; Thomas L Rothstein; Thomas C Chiles
Journal: Immunol Res Date: 2003 Impact factor: 2.829

4. Complementary costimulation of human T-cell subpopulations by cluster of differentiation 28 (CD28) and CD81.

Authors: Yael Sagi; Angela Landrigan; Ronald Levy; Shoshana Levy
Journal: Proc Natl Acad Sci U S A Date: 2012-01-17 Impact factor: 11.205

5. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.

Authors: S Ramaswamy; N Nakamura; F Vazquez; D B Batt; S Perera; T M Roberts; W R Sellers
Journal: Proc Natl Acad Sci U S A Date: 1999-03-02 Impact factor: 11.205

10. Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle.

Authors: Douglas R Bolster; Neil Kubica; Stephen J Crozier; David L Williamson; Peter A Farrell; Scot R Kimball; Leonard S Jefferson
Journal: J Physiol Date: 2003-08-22 Impact factor: 5.182

Translation control: connecting mitogens and the ribosome.

1. Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.

2. Impaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker rat.

Review 3. Cell cycle control mechanisms in B-1 and B-2 lymphoid subsets.

4. Complementary costimulation of human T-cell subpopulations by cluster of differentiation 28 (CD28) and CD81.

5. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.

6. Mitotic lymphoma cells are characterized by high expression of phosphorylated ribosomal S6 protein.

7. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.

8. A characterization and targeting of the infarct border zone in a swine model of myocardial infarction.

9. Identification of a novel small molecule HIF-1alpha translation inhibitor.

10. Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle.