| Literature DB >> 9544932 |
M Igarashi1, T Tsuchida, N Kinoshita, M Kamijima, R Sawa, T Sawa, H Naganawa, M Hamada, T Takeuchi, K Yamazaki, M Ishizuka.
Abstract
A novel 19-membered macrocyclic lactam antibiotic, cremimycin, was isolated from the culture broth of an actinomycete strain. The producing organism, designated MJ635-86F5, was identified as a member of Streptomyces. Cremimycin was isolated from the mycelial cake by extraction with CHCl3-MeOH and precipitation with hexane-MeOH. The structure of cremimycin was determined by spectroscopic study. Cremimycin showed broad antimicrobial activities against Gram-positive bacteria including MRSA.Entities:
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Year: 1998 PMID： 9544932 DOI： 10.7164/antibiotics.51.123
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649