Literature DB >> 9544565

HIV-inhibitory and cytotoxic oligostilbenes from the leaves of Hopea malibato.

J R Dai1, Y F Hallock, J H Cardellina, M R Boyd.   

Abstract

Three new oligostilbenes, malibatols A (1) and B (2) and dibalanocarpol (3), together with one known oligostilbene balanocarpol (4), were isolated from the organic extract of the leaves of Hopea malibato. The structure elucidation of these compounds was based on the interpretation of their chemical and spectral data. Compounds 3 and 4 exhibited very modest HIV-inhibitory activity, while compounds 1 and 2 were cytotoxic to the host cells (CEM SS) in the antiviral assay.

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Year:  1998        PMID: 9544565     DOI: 10.1021/np970519h

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  14 in total

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