Literature DB >> 9540269

Give us this day our daily germs.

G A Rook1, J L Stanford.   

Abstract

Modern vaccinations, fear of germs and obsession with hygiene are depriving the immune system of the information input upon which it is dependent. This fails to maintain the correct cytokine balance and fine-tune T-cell regulation, and may lead to increased incidences of allergies and autoimmune diseases. If humans continue to deprive their immune systems of the input to which evolution has adapted it, it may be necessary to devise ways of replacing it artificially.

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Mesh:

Year:  1998        PMID: 9540269     DOI: 10.1016/s0167-5699(97)01204-8

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  71 in total

Review 1.  Type 1 and type 2 immune responses in children: their relevance in juvenile arthritis.

Authors:  L R Wedderburn; P Woo
Journal:  Springer Semin Immunopathol       Date:  1999

2.  Non-specific effects of vaccines in developing countries. We need evidence about the effect of vaccines on mortality from all causes.

Authors:  F Shann
Journal:  BMJ       Date:  2000-12-09

Review 3.  Family size, infection and atopy: the first decade of the "hygiene hypothesis".

Authors:  D P Strachan
Journal:  Thorax       Date:  2000-08       Impact factor: 9.139

Review 4.  The maternal-neonatal neuro-immune interface: are there long-term implications for inflammatory or stress-related disease?

Authors:  N Shanks; S L Lightman
Journal:  J Clin Invest       Date:  2001-12       Impact factor: 14.808

Review 5.  Interference of antibacterial agents with phagocyte functions: immunomodulation or "immuno-fairy tales"?

Authors:  M T Labro
Journal:  Clin Microbiol Rev       Date:  2000-10       Impact factor: 26.132

6.  Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens.

Authors:  E J Ryan; L Nilsson; N Kjellman; L Gothefors; K H Mills
Journal:  Clin Exp Immunol       Date:  2000-08       Impact factor: 4.330

7.  Home dampness, current allergic diseases, and respiratory infections among young adults.

Authors:  M Kilpeläinen; E O Terho; H Helenius; M Koskenvuo
Journal:  Thorax       Date:  2001-06       Impact factor: 9.139

Review 8.  New approaches to investigating heterogeneity in complex traits.

Authors:  R Bomprezzi; P E Kovanen; R Martin
Journal:  J Med Genet       Date:  2003-08       Impact factor: 6.318

Review 9.  Vaccination strategies to reduce the risk of leukaemia and melanoma.

Authors:  John M Grange; John L Stanford; Cynthia A Stanford; Klaus F Kölmel
Journal:  J R Soc Med       Date:  2003-08       Impact factor: 5.344

10.  Anti-inflammatory and immunomodulatory effect of an extract of Coccidioides posadasii in experimental arthritis.

Authors:  Ana Carolina Matias Dinelly Pinto; Rossana de Aguiar Cordeiro; José Julio Costa Sidrim; Ana Karine Rocha de Melo Leite; Ana Caroline Rocha de Melo Leite; Virgínia Cláudia Carneiro Girão; Raimunda Sâmia Nogueira Brilhante; Marcos Fábio Gadelha Rocha; Fernando de Queiroz Cunha; Francisco Airton Castro Rocha
Journal:  Mycopathologia       Date:  2013-02-05       Impact factor: 2.574

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