| Literature DB >> 953934 |
T S Ing, S D Mahurkar, G Dunea, J A Hayashi, H L Klawans, W S Markey.
Abstract
Two patients with Parkinson's disease and renal insufficiency had excessively high concentrations of amantadine hydrochloride in the blood. The amounts of the drug removed by hemodialysis and peritoneal dialysis were small. However, since extrarenal elimination is negligible in such patients, frequently repeated dialysis may be required to remove the drug.Entities:
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Year: 1976 PMID： 953934 PMCID： PMC1878764
Source DB: PubMed Journal: Can Med Assoc J ISSN： 0008-4409 Impact factor: 8.262