Literature DB >> 9538687

The role of the ribosome-translocon complex in translation and assembly of polytopic membrane proteins.

E Bibi1.   

Abstract

Newly synthesized polytopic membrane proteins and secretory proteins often share the same target membrane as their primary destination, and in some cases, the cellular machinery that targets and transfers them into or across the membrane. Unlike secretory proteins, which are localized to the external compartment, each polytopic membrane protein molecule must be partitioned among the cytoplasm, the membrane and the external milieu. How does the ribosome-translocon complex cope with the different domains of polytopic membrane proteins?

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Year:  1998        PMID: 9538687     DOI: 10.1016/s0968-0004(97)01134-1

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  11 in total

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