Literature DB >> 9537747

Advances in DNA diagnostics.

J H Graber1, M J O'Donnell, C L Smith, C R Cantor.   

Abstract

The key advances in DNA diagnostics during the past year are techniques which will lead to advanced throughput without sacrificing sensitivity: miniaturization of samples to reduce material cost and preparation time, and parallelization through use of measurement arrays. The most promising gains have come in the areas of DNA arrays and mass spectrometry, where differential sequencing measurements are now possible.

Mesh:

Year:  1998        PMID: 9537747     DOI: 10.1016/s0958-1669(98)80078-5

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  3 in total

1.  Mass spectrometry of single-stranded restriction fragments captured by an undigested complementary sequence.

Authors:  N H Chiu; K Tang; P Yip; A Braun; H Koster; C R Cantor
Journal:  Nucleic Acids Res       Date:  2000-04-15       Impact factor: 16.971

2.  Analysis of short tandem repeat polymorphisms by electrospray ion trap mass spectrometry.

Authors:  S Hahner; A Schneider; A Ingendoh; J Mosner
Journal:  Nucleic Acids Res       Date:  2000-09-15       Impact factor: 16.971

3.  Determination of single-nucleotide polymorphisms by real-time pyrophosphate DNA sequencing.

Authors:  A Alderborn; A Kristofferson; U Hammerling
Journal:  Genome Res       Date:  2000-08       Impact factor: 9.043

  3 in total

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