Literature DB >> 9537492

Thymic cyst haemorrhages and transient cholestasis in a 4-week-old infant.

L P Koopman1, F B Plötz, J J Meuzelaar, H Knoester.   

Abstract

UNLABELLED: We report a 4-week-old boy with acute respiratory distress, due to massive haemorrhages in multiple thymic cysts. A right hemithymectomy was performed because of mechanical obstruction of the trachea by the cysts. The origin of the multilocular thymic cysts remained unclear. Most likely, these haemorrhages were caused by vitamin K deficiency, although the infant received vitamin K prophylaxis. In addition, he developed transient cholestasis, but the aetiology remained unclear. It is postulated that massive haemorrhages in thymic cysts produce large amounts of bilirubin, causing sludging of bile excretions in the liver. Four weeks after the operation, all laboratory findings were normal and 6 months after the operation the boy is still healthy.
CONCLUSION: This case report shows that respiratory distress in an infant can be caused by multiple haemorrhages in multilocular thymic cysts.

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Year:  1998        PMID: 9537492     DOI: 10.1007/s004310050802

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  2 in total

1.  Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding.

Authors:  S P Pereira; M J Shearer; R Williams; G Mieli-Vergani
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2003-03       Impact factor: 5.747

2.  Spontaneous thymic cyst hemorrhage causing hemothorax.

Authors:  Kiyoshi Ohno; Tomoki Utsumi; Yoshiaki Sasaki; Yuko Suzuki
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2003-11
  2 in total

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