AIM: To measure changes in cerebral haemodynamics over the first three days of life in very preterm infants with normal brains. METHODS: Eleven mechanically ventilated infants (median gestational age 26 weeks) without evidence of major abnormalities on cranial ultrasound examination were studied. Cerebral blood flow (CBF) and cerebral blood volume (CBV) were measured using near infrared spectroscopy at least twice over the first three days of life. RESULTS: Cerebral blood flow increased significantly with time (p = 0.02; stepwise linear regression) and this was independent of mean arterial blood pressure, PaCO2, and haematocrit. CONCLUSION: This change is likely to represent a normal adaptive response of the cerebral circulation to postnatal life.
AIM: To measure changes in cerebral haemodynamics over the first three days of life in very preterm infants with normal brains. METHODS: Eleven mechanically ventilated infants (median gestational age 26 weeks) without evidence of major abnormalities on cranial ultrasound examination were studied. Cerebral blood flow (CBF) and cerebral blood volume (CBV) were measured using near infrared spectroscopy at least twice over the first three days of life. RESULTS: Cerebral blood flow increased significantly with time (p = 0.02; stepwise linear regression) and this was independent of mean arterial blood pressure, PaCO2, and haematocrit. CONCLUSION: This change is likely to represent a normal adaptive response of the cerebral circulation to postnatal life.
Authors: Minhui Ouyang; Peiying Liu; Tina Jeon; Lina Chalak; Roy Heyne; Nancy K Rollins; Daniel J Licht; John A Detre; Timothy P L Roberts; Hanzhang Lu; Hao Huang Journal: Neuroimage Date: 2016-12-14 Impact factor: 6.556
Authors: Tim Schindler; Yasmin Gilbert; Sonali Jayatilake; Gordon Stevenson; Ju Lee Oei; Alec Welsh Journal: Pediatr Res Date: 2016-05-16 Impact factor: 3.756
Authors: Nadège Roche-Labarbe; Stefan A Carp; Andrea Surova; Megha Patel; David A Boas; P Ellen Grant; Maria Angela Franceschini Journal: Hum Brain Mapp Date: 2010-03 Impact factor: 5.038