Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 2-methyl-3-acetyl-4-aryl-5-oxo-1,4-dihydro-5H indeno(1,2-b) pyridine derivatives studies and their calcium antagonistic activities.

2-methyl-3-acetyl-4-aryl-5-oxo-1,4-dihydro-5H indeno(1,2-b) pyridine derivatives studies and their calcium antagonistic activities.

C Safak¹, R Simsek, Y Altas, S Boydag, K Erol.

Abstract

Sixteen 2-methyl-3-acetyl-4-aryl-5-oxo-1,4-dihydro-5H-indeno(1,2-b)pyridine derivatives (3a-p) have been prepared. The structures of the compounds were characterised by IR, 1H-NMR, 13C-NMR, X-Ray and elemental analyses. The calcium antagonistic activity of these compounds were studied in rat taenia coli pre-contracted with 1 mmol/l Ca+2.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1997 PMID： 9534263

Source DB: PubMed Journal: Boll Chim Farm ISSN： 0006-6648

2-methyl-3-acetyl-4-aryl-5-oxo-1,4-dihydro-5H indeno(1,2-b) pyridine derivatives studies and their calcium antagonistic activities.

1. Construction of Dispiro-Indenone Scaffolds via Domino Cycloaddition Reactions of α,β-Unsaturated Aldimines with 2-Arylidene-1,3-indenediones and 2,2'-(Arylmethylene)bis(1,3-indenediones).

2. A straightforward, environmentally beneficial synthesis of spiro[diindeno[1,2-b:2',1'-e]pyridine-11,3'-indoline]-2',10,12-triones mediated by a nano-ordered reusable catalyst.