Literature DB >> 9531470

Cloning of a functional promoter of the human sodium/iodide-symporter gene.

M Behr1, T L Schmitt, C R Espinoza, U Loos.   

Abstract

We have cloned and sequenced genomic DNA from a human library extending 1300 bp upstream the 5'-untranslated sequence of the cDNA coding for the sodium/iodide symporter. In transient transfection assays this sequence exhibited promoter activity, which could be confined to nucleotides -443 to -395 relative to the ATG start codon. This minimal promoter, including a putative GC- and TATA- box, was preferentially activated in the rat thyroid cell line FRTL-5, but was also active in non-thyroidal cells, such as COS-7 and Chinese-hamster ovary, albeit to a markedly lower extent.

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Year:  1998        PMID： 9531470      PMCID： PMC1219361          DOI： 10.1042/bj3310359

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  Increased expression of the Na+/I- symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue.

Authors:  T Saito; T Endo; A Kawaguchi; M Ikeda; M Nakazato; T Kogai; T Onaya
Journal:  J Clin Endocrinol Metab       Date:  1997-10       Impact factor: 5.958

2.  Thyroid transcription factor-1 activates the promoter activity of rat thyroid Na+/I- symporter gene.

Authors:  T Endo; M Kaneshige; M Nakazato; M Ohmori; N Harii; T Onaya
Journal:  Mol Endocrinol       Date:  1997-10

3.  Promoter characterization of the rat Na+/I- symporter gene.

Authors:  Q Tong; K Y Ryu; S M Jhiang
Journal:  Biochem Biophys Res Commun       Date:  1997-10-09       Impact factor: 3.575

Review 4.  CpG islands and genes.

Authors:  S H Cross; A P Bird
Journal:  Curr Opin Genet Dev       Date:  1995-06       Impact factor: 5.578

5.  Deoxyribonucleic acid binding and transcriptional silencing by a truncated c-erbA beta 1 thyroid hormone receptor identified in a severely retarded patient with resistance to thyroid hormone.

Authors:  M Behr; D B Ramsden; U Loos
Journal:  J Clin Endocrinol Metab       Date:  1997-04       Impact factor: 5.958

6.  Culture of hormone-dependent functional epithelial cells from rat thyroids.

Authors:  F S Ambesi-Impiombato; L A Parks; H G Coon
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

Review 7.  Thyroid-specific gene expression.

Authors:  G Damante; R Di Lauro
Journal:  Biochim Biophys Acta       Date:  1994-08-02

8.  Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter.

Authors:  P A Smanik; K Y Ryu; K S Theil; E L Mazzaferri; S M Jhiang
Journal:  Endocrinology       Date:  1997-08       Impact factor: 4.736

9.  Cloning and characterization of the thyroid iodide transporter.

Authors:  G Dai; O Levy; N Carrasco
Journal:  Nature       Date:  1996-02-01       Impact factor: 49.962

10.  Characterization of an up-stream thyroid transcription factor-1-binding site in the thyrotropin receptor promoter.

Authors:  M Ohmori; H Shimura; Y Shimura; S Ikuyama; L D Kohn
Journal:  Endocrinology       Date:  1995-01       Impact factor: 4.736
View more
  10 in total

Review 1.  Regulation of sodium/iodide symporter.

Authors:  S M Jhiang
Journal:  Rev Endocr Metab Disord       Date:  2000-04       Impact factor: 6.514

Review 2.  The biology of the sodium iodide symporter and its potential for targeted gene delivery.

Authors:  Mohan Hingorani; Christine Spitzweg; Georges Vassaux; Kate Newbold; Alan Melcher; Hardev Pandha; Richard Vile; Kevin Harrington
Journal:  Curr Cancer Drug Targets       Date:  2010-03       Impact factor: 3.428

3.  Efficacy of 99mTc pertechnetate and 131I radioisotope therapy in sodium/iodide symporter (NIS)-expressing neuroendocrine tumors in vivo.

Authors:  Meike L Schipper; Christoph G U Riese; Stephan Seitz; Alexander Weber; Martin Béhé; Tino Schurrat; Nils Schramm; Boris Keil; Heiko Alfke; Thomas M Behr
Journal:  Eur J Nucl Med Mol Imaging       Date:  2006-12-08       Impact factor: 9.236

4.  Intronic elements in the Na+/I- symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription.

Authors:  Hani Alotaibi; Elif Yaman; Domenico Salvatore; Valeria Di Dato; Pelin Telkoparan; Roberto Di Lauro; Uygar H Tazebay
Journal:  Nucleic Acids Res       Date:  2010-01-31       Impact factor: 16.971

5.  Transcription factor Nkx-2.5 induces sodium/iodide symporter gene expression and participates in retinoic acid- and lactation-induced transcription in mammary cells.

Authors:  Monica Dentice; Cristina Luongo; Antonia Elefante; Romina Romino; Raffaele Ambrosio; Mario Vitale; Guido Rossi; Gianfranco Fenzi; Domenico Salvatore
Journal:  Mol Cell Biol       Date:  2004-09       Impact factor: 4.272

6.  The potential of 211Astatine for NIS-mediated radionuclide therapy in prostate cancer.

Authors:  Michael J Willhauck; Bibi-Rana Sharif Samani; Ingo Wolf; Reingard Senekowitsch-Schmidtke; Hans-Jürgen Stark; Geerd J Meyer; Wolfram H Knapp; Burkhard Göke; John C Morris; Christine Spitzweg
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-04-11       Impact factor: 9.236

7.  The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription.

Authors:  M Ohno; M Zannini; O Levy; N Carrasco; R di Lauro
Journal:  Mol Cell Biol       Date:  1999-03       Impact factor: 4.272

8.  HEX expression and localization in normal mammary gland and breast carcinoma.

Authors:  Cinzia Puppin; Fabio Puglisi; Lucia Pellizzari; Guidalberto Manfioletti; Marta Pestrin; Maura Pandolfi; Andrea Piga; Carla Di Loreto; Giuseppe Damante
Journal:  BMC Cancer       Date:  2006-07-19       Impact factor: 4.430

9.  Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

Authors:  Eusebio Chiefari; Antonio Brunetti; Franco Arturi; Jean-Michel Bidart; Diego Russo; Martin Schlumberger; Sebastiano Filetti
Journal:  BMC Cancer       Date:  2002-12-10       Impact factor: 4.430

10.  The Thyroid Na+/I- Symporter: Molecular Characterization and Genomic Regulation.

Authors:  Hani Alotaibi; Merve Tuzlakoğlu-Öztürk; Uygar Halis Tazebay
Journal:  Mol Imaging Radionucl Ther       Date:  2017-02-09
  10 in total

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