Literature DB >> 9529959

Germinoma of the basal ganglia and thalamus--CT and MRI findings.

L W Wong1, C R Jayakumar.   

Abstract

A case of germinoma originating in the basal ganglia and thalamus is presented. This tumour most commonly originates during childhood and adolescence, at pineal and suprasellar regions. In the early stages, the diagnosis of germinoma in the basal ganglion and thalamus is difficult because of its rarity and non-specific findings. The computed tomography (CT) and magnetic resonance imaging (MRI) findings though non-diagnostic, are discussed here. A few differential diagnoses had been discussed with radiological abnormality. Open biopsy done in this case proved to be two-cell pattern germinoma. Early detection of the tumour is desirable, since this tumour is highly sensitive to radio and chemotherapy and is potentially curable. Our patient was treated with combined chemotherapy and the response was well and no residual tumour or recurrence was seen on the repeated imaging modality, however his neurological deficits remained unchanged.

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Year:  1997        PMID: 9529959

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


  4 in total

1.  Inherent diagnostic and treatment challenges in germinoma of the basal ganglia: a case report and review of the literature.

Authors:  Anita Villani; Eric Bouffet; Susan Blaser; Barbara-Ann Millar; Cynthia Hawkins; Ute Bartels
Journal:  J Neurooncol       Date:  2008-03-26       Impact factor: 4.130

2.  The germinomas arising from the basal ganglia and thalamus.

Authors:  Jie Tang; Zhenyu Ma; Shiqi Luo; Yuqi Zhang; Ge Jia; Junting Zhang
Journal:  Childs Nerv Syst       Date:  2007-09-19       Impact factor: 1.475

3.  Germinoma involving the basal ganglia in children.

Authors:  Tai-Tong Wong; Y W Chen; Wan-Yuo Guo; Kai-Ping Chang; Donald M Ho; Sang-Hue Yen
Journal:  Childs Nerv Syst       Date:  2007-09-29       Impact factor: 1.475

Review 4.  Radiologic features of primary intracranial ectopic germinomas: Case reports and literature review.

Authors:  Xin-Hua Wei; Hui-Cong Shen; Shou-Xian Tang; Cui-Hua Gao; Ji-Liang Ren; Lin Ai; Jian-Ping Dai
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.889

  4 in total

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