Literature DB >> 952987

Metabolism of 8,11,14-eicosatrienoic acid in human platelets.

P Falardeau, M Hamberg, B Samuelsson.   

Abstract

The following labeled compounds were isolated and identified after incubation of 8,11,14-eicosatrien [1-14C] oic acid with human platelets: 12-L-hydroxy-8,10,14-eicosatrienoic acid, 8,11,12-trihydroxy-9,14-eicosadienoic acid, 8,9,12-trihydroxy-10,14-eicosadienoic acid, 12-L-hydroxy-8,10-heptadecadienoic acid, prostaglandin E1, prostaglandin D1, and 8-(1-hydroxy-3-oxopropyl)-9,12-dihydroxy-10-heptadecenoic acid (thromboxane B1).

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Year:  1976        PMID： 952987     DOI： 10.1016/0005-2760(76)90162-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  14 in total

1.  Plasma and mucosal fatty acid pattern in colectomized ulcerative colitis patients.

Authors:  M Esteve; E Navarro; J Klaassen; A Abad-Lacruz; F González-Huix; E Cabré; E Ramos; E Condom; F Fernández-Bañares; C Pastor; P Humbert; J Martí-Ragué; M A Gassull
Journal:  Dig Dis Sci       Date:  1998-05       Impact factor: 3.199

2.  12(S)-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in Platelets.

Authors:  Jennifer Yeung; Benjamin E Tourdot; Reheman Adili; Abigail R Green; Cody J Freedman; Pilar Fernandez-Perez; Johnny Yu; Theodore R Holman; Michael Holinstat
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-07-28       Impact factor: 8.311

3.  Abnormal plasma polyunsaturated fatty acid pattern in non-active inflammatory bowel disease.

Authors:  M Esteve-Comas; M C Núñez; F Fernández-Bañares; A Abad-Lacruz; A Gil; E Cabré; F González-Huix; X Bertrán; M A Gassull
Journal:  Gut       Date:  1993-10       Impact factor: 23.059

4.  Prostaglandin endoperoxides and thromboxanes: formation and effects.

Authors:  S Moncada
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977       Impact factor: 3.000

Review 5.  The prostanoids in hemostasis and thrombosis: a review.

Authors:  J B Smith
Journal:  Am J Pathol       Date:  1980-06       Impact factor: 4.307

6.  Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187.

Authors:  P Borgeat; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

7.  Changes in plasma and colonic mucosa fatty acid profiles in rats with ulcerative colitis induced by trinitrobenzene sulfonic acid.

Authors:  N Nieto; M D Giron; M D Suarez; A Gil
Journal:  Dig Dis Sci       Date:  1998-12       Impact factor: 3.199

8.  Linoleic acid-induced fatty acid changes in platelet and aorta of the rat: effect of age and cholesterol.

Authors:  R Takahashi; D F Horrobin
Journal:  Lipids       Date:  1988-09       Impact factor: 1.880

9.  Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation.

Authors:  Kenneth N Ikei; Jennifer Yeung; Patrick L Apopa; Jesús Ceja; Joanne Vesci; Theodore R Holman; Michael Holinstat
Journal:  J Lipid Res       Date:  2012-09-13       Impact factor: 5.922

10.  A second pathway of leukotriene biosynthesis in porcine leukocytes.

Authors:  R L Maas; A R Brash; J A Oates
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205
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