| Literature DB >> 9527813 |
A Musafija1, A Barzilai, J Ramon, E Rubinstein.
Abstract
The transepithelial intestinal elimination of ciprofloxacin (CPX) was studied in cholera toxin (CT)-challenged and control intestinal loops in the rabbit. CPX concentrations were similar in CT-challenged and control jejunal and ileal loops, while cecal elimination was negligible. The quantities of eliminated CPX per square centimeter of bowel wall were significantly higher in the small intestine CT-challenged loops. The mechanism of elimination of CPX in the small intestine is therefore mainly passive diffusion.Entities:
Mesh：
Substances：
Year: 1998 PMID： 9527813 PMCID： PMC105441 DOI： 10.1128/AAC.42.2.473
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191