C W Spraul1, H E Grossniklaus, G K Lang. 1. L. F. Montgomery Eye Pathology Laboratory, Emory University School of Medicine Atlanta, GA, USA.
Abstract
PATIENT: A 62-year-old woman was evaluated for a bilateral subconjunctival mass that had been present for 6 months. With magnetic resonance imaging the lesion could not be delineated form the lacrimal glands. A biopsy was performed and histologic examination exhibited a xanthogranulomatous lesion with multiple giant-cells of the Touton type. The differential diagnosis of the adult xanthogranuloma is Erdheim-Chester disease, necrobiotic granuloma, xanthoma, Langerhans histiocytosis, and Rosai-Dorfman syndrome. CONCLUSION: Hyperlipemia should be excluded, in addition, in the presence of necrobiosis, paraproteinemia.
PATIENT: A 62-year-old woman was evaluated for a bilateral subconjunctival mass that had been present for 6 months. With magnetic resonance imaging the lesion could not be delineated form the lacrimal glands. A biopsy was performed and histologic examination exhibited a xanthogranulomatous lesion with multiple giant-cells of the Touton type. The differential diagnosis of the adult xanthogranuloma is Erdheim-Chester disease, necrobiotic granuloma, xanthoma, Langerhans histiocytosis, and Rosai-Dorfman syndrome. CONCLUSION:Hyperlipemia should be excluded, in addition, in the presence of necrobiosis, paraproteinemia.