PURPOSE: To evaluate the pseudoexfoliation (PEX) prevalence in the island of Crete (Greece). METHOD: Organized visits to various villages, to examine a predetermined number of people born and living in these villages, in collaboration with the local birth register offices. RESULTS: PEX prevalence in Crete, in people aged 40 years and more, was found to be 16.1% (men: 21.3%, women: 12.6% - Prefecture of: Heraklion 11.5%, Chania 13.4%, Lasithi 16.9%, Rethymnon 27%). 28.8% of PEX-patients presented IOP > 21 mmHg. In unilateral PEX-patients, mean IOP of PEX-eyes was found to be 17.82 mmHg versus 15.6 mmHg in fellow eyes. CONCLUSION: PEX prevalence was higher in men than in women and increases with age, as does bilaterality. A correlation between increased PEX prevalence and high altitude may exist. PEX is a risk factor for the development of IOP disturbances which seem to appear earlier in women.
PURPOSE: To evaluate the pseudoexfoliation (PEX) prevalence in the island of Crete (Greece). METHOD: Organized visits to various villages, to examine a predetermined number of people born and living in these villages, in collaboration with the local birth register offices. RESULTS: PEX prevalence in Crete, in people aged 40 years and more, was found to be 16.1% (men: 21.3%, women: 12.6% - Prefecture of: Heraklion 11.5%, Chania 13.4%, Lasithi 16.9%, Rethymnon 27%). 28.8% of PEX-patients presented IOP > 21 mmHg. In unilateral PEX-patients, mean IOP of PEX-eyes was found to be 17.82 mmHg versus 15.6 mmHg in fellow eyes. CONCLUSION: PEX prevalence was higher in men than in women and increases with age, as does bilaterality. A correlation between increased PEX prevalence and high altitude may exist. PEX is a risk factor for the development of IOP disturbances which seem to appear earlier in women.
Authors: R R Allingham; M Loftsdottir; M S Gottfredsdottir; E Thorgeirsson; F Jonasson; T Sverisson; W G Hodge; K F Damji; E Stefánsson Journal: Br J Ophthalmol Date: 2001-06 Impact factor: 4.638
Authors: K F Damji; A G P Konstas; J M Liebmann; W G Hodge; N G Ziakas; S Giannikakis; G Mintsioulis; A Merkur; Y Pan; R Ritch Journal: Br J Ophthalmol Date: 2006-05-03 Impact factor: 4.638