Literature DB >> 9523104

An ancient system of host defense.

R Medzhitov1, C A Janeway.   

Abstract

Research over the past few years has begun to provide significant advances in our understanding of the interplay between the innate and adaptive immune systems. New findings in several model systems reveal remarkable parallels and conservation of ancient host defense pathways in organisms separated by over a billion years of evolution.

Mesh：

Year:  1998        PMID： 9523104     DOI： 10.1016/s0952-7915(98)80024-1

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  67 in total

1.  Three-dimensional structure of a complex between the death domains of Pelle and Tube.

Authors:  T Xiao; P Towb; S A Wasserman; S R Sprang
Journal:  Cell       Date:  1999-11-24       Impact factor: 41.582

Review 2.  Regulation of inducible gene expression by the transcription factor NF-kappaB.

Authors:  S Ghosh
Journal:  Immunol Res       Date:  1999       Impact factor: 2.829

Review 3.  Genetics of mosquito vector competence.

Authors:  B T Beerntsen; A A James; B M Christensen
Journal:  Microbiol Mol Biol Rev       Date:  2000-03       Impact factor: 11.056

Review 4.  Control of immune pathology by IL-10-secreting regulatory T cells.

Authors:  S Fowler; F Powrie
Journal:  Springer Semin Immunopathol       Date:  1999

5.  ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor.

Authors:  N McNamara; A Khong; D McKemy; M Caterina; J Boyer; D Julius; C Basbaum
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

Review 6.  What is the 'true' function of skin?

Authors:  C M Chuong; B J Nickoloff; P M Elias; L A Goldsmith; E Macher; P A Maderson; J P Sundberg; H Tagami; P M Plonka; K Thestrup-Pederson; B A Bernard; J M Schröder; P Dotto; C M Chang; M L Williams; K R Feingold; L E King; A M Kligman; J L Rees; E Christophers
Journal:  Exp Dermatol       Date:  2002-04       Impact factor: 3.960

Review 7.  Once a killer, always a killer: from cytotoxic T cell to memory cell.

Authors:  Leo Lefrançois; Joshua J Obar
Journal:  Immunol Rev       Date:  2010-05       Impact factor: 12.988

8.  The GATA factor Serpent is required for the onset of the humoral immune response in Drosophila embryos.

Authors:  T O Tingvall; E Roos; Y Engström
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-06       Impact factor: 11.205

9.  Adaptive innate immunity? Responsive-mode prophylaxis in the mealworm beetle, Tenebrio molitor.

Authors:  Yannick Moret; Michael T Siva-Jothy
Journal:  Proc Biol Sci       Date:  2003-12-07       Impact factor: 5.349

Review 10.  Variation in immune defence as a question of evolutionary ecology.

Authors:  Paul Schmid-Hempel
Journal:  Proc Biol Sci       Date:  2003-02-22       Impact factor: 5.349
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