Literature DB >> 9521380

Use of corticosteroids by Australian obstetricians--a survey of clinical practice.

J A Quinlivan1, S F Evans, S A Dunlop, L D Beazley, J P Newnham.   

Abstract

All Fellows, Members and trainees of the Royal Australian College of Obstetricians and Gynaecologists resident in Australia (n= 1,281) received a questionnaire relating to their practice of prescribing antenatal corticosteroids. 833 (65%) responded. The key findings were that 97% of Australian obstetricians prescribe antenatal corticosteroids in the classical setting of uncomplicated early preterm labour and 85% prescribe repeated courses in those cases in which the risk of preterm birth persists or recurs; 50% of obstetricians prescribe this agent weekly in cases with persisting risk of preterm birth. Some of the prescribing practices were found to be related to the number of years since obtaining specialist qualification. In view of the widespread clinical use of repeated doses of corticosteroids revealed in this present survey, it is clear that further research is warranted to determine the possible benefits and hazards of repeated exposures of the developing fetus to this therapy.

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Year:  1998        PMID: 9521380     DOI: 10.1111/j.1479-828x.1998.tb02947.x

Source DB:  PubMed          Journal:  Aust N Z J Obstet Gynaecol        ISSN: 0004-8666            Impact factor:   2.100


  18 in total

1.  Antenatal corticosteroids to prevent neonatal respiratory distress syndrome. We do not know whether repeated doses are better than a single dose.

Authors:  C Spencer; K Neales
Journal:  BMJ       Date:  2000-02-05

Review 2.  Fetal programming of hypothalamo-pituitary-adrenal function: prenatal stress and glucocorticoids.

Authors:  Amita Kapoor; Elizabeth Dunn; Alice Kostaki; Marcus H Andrews; Stephen G Matthews
Journal:  J Physiol       Date:  2006-02-09       Impact factor: 5.182

Review 3.  Decline in effectiveness of antenatal corticosteroids with time to birth: real or artefact?

Authors:  Simon Gates; Peter Brocklehurst
Journal:  BMJ       Date:  2007-07-14

4.  Repeated betamethasone treatment of pregnant sheep programs persistent reductions in circulating IGF-I and IGF-binding proteins in progeny.

Authors:  Kathryn L Gatford; Julie A Owens; Shaofu Li; Timothy J M Moss; John P Newnham; John R G Challis; Deborah M Sloboda
Journal:  Am J Physiol Endocrinol Metab       Date:  2008-05-20       Impact factor: 4.310

Review 5.  Glucocorticoids and fetal programming part 1: Outcomes.

Authors:  Vasilis G Moisiadis; Stephen G Matthews
Journal:  Nat Rev Endocrinol       Date:  2014-05-27       Impact factor: 43.330

6.  Repeated maternal glucocorticoid treatment affects activity and hippocampal NMDA receptor expression in juvenile guinea pigs.

Authors:  Dawn Owen; Stephen G Matthews
Journal:  J Physiol       Date:  2006-10-26       Impact factor: 5.182

7.  Repeated courses of antenatal corticosteroids have adverse effects on aspects of brain development in naturally delivered baboon infants.

Authors:  Amy Shields; Merran Thomson; Vicki Winter; Jacqueline Coalson; Sandra Rees
Journal:  Pediatr Res       Date:  2012-02-14       Impact factor: 3.756

8.  Repeated antenatal corticosteroid treatments adversely affect neural transmission time and auditory thresholds in laboratory rats.

Authors:  M W Church; B R Adams; J I Anumba; D A Jackson; M L Kruger; K-L C Jen
Journal:  Neurotoxicol Teratol       Date:  2011-09-22       Impact factor: 3.763

Review 9.  Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth.

Authors:  Fiona C Brownfoot; Caroline A Crowther; Philippa Middleton
Journal:  Cochrane Database Syst Rev       Date:  2008-10-08

10.  Prenatal synthetic glucocorticoid exposure alters hypothalamic-pituitary-adrenal regulation and pregnancy outcomes in mature female guinea pigs.

Authors:  Elizabeth Dunn; Amita Kapoor; Jason Leen; Stephen G Matthews
Journal:  J Physiol       Date:  2010-01-11       Impact factor: 5.182

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