Literature DB >> 9521275

Testosterone versus testosterone and testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism.

A G Herzog1, P Klein, A R Jacobs.   

Abstract

Antiepileptic drug-induced reductions in serum levels of biologically active testosterone and elevations in serum estradiol (E2) may contribute to sexual dysfunction among men with epilepsy. Treatment using a combination of testosterone and the aromatase inhibitor testolactone may have significantly better effects on sexual function and also seizure frequency than testosterone alone.

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Year:  1998        PMID: 9521275     DOI: 10.1212/wnl.50.3.782

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  9 in total

1.  Sex hormones and epilepsy: no longer just for women.

Authors:  Susan Herman
Journal:  Epilepsy Curr       Date:  2008 Jan-Feb       Impact factor: 7.500

Review 2.  Hormonal therapy for epilepsy.

Authors:  Scott J Stevens; Cynthia L Harden
Journal:  Curr Neurol Neurosci Rep       Date:  2011-08       Impact factor: 5.081

3.  Associations between urinary polycyclic aromatic hydrocarbon metabolites and serum testosterone in U.S. adult males: National Health and nutrition examination survey 2011-2012.

Authors:  Lingling Wang; Weiyue Hu; Yankai Xia; Xinru Wang
Journal:  Environ Sci Pollut Res Int       Date:  2017-01-24       Impact factor: 4.223

Review 4.  Epilepsy Care in Transgender Patients.

Authors:  Genna Waldman; Rachael Benson
Journal:  Curr Neurol Neurosci Rep       Date:  2022-06-06       Impact factor: 6.030

Review 5.  Alternative treatment modalities for the hypogonadal patient.

Authors:  Landon W Trost; Mohit Khera
Journal:  Curr Urol Rep       Date:  2014-07       Impact factor: 3.092

6.  Mass spectrometric assay and physiological-pharmacological activity of androgenic neurosteroids.

Authors:  Doodipala S Reddy
Journal:  Neurochem Int       Date:  2007-06-13       Impact factor: 3.921

7.  The acute effects of exercise on cortical excitation and psychosocial outcomes in men treated for prostate cancer: a randomized controlled trial.

Authors:  Daniel Santa Mina; Crissa L Guglietti; Danilo R de Jesus; Saam Azargive; Andrew G Matthew; Shabbir M H Alibhai; John Trachtenberg; Jeffrey Z Daskalakis; Paul Ritvo
Journal:  Front Aging Neurosci       Date:  2014-11-26       Impact factor: 5.750

8.  Improvement of GAD65-associated autoimmune epilepsy with testosterone replacement therapy.

Authors:  Melissa Heiry; Pegah Afra; Fumisuke Matsuo; John E Greenlee; Stacey L Clardy
Journal:  Neurol Neuroimmunol Neuroinflamm       Date:  2015-08-13

9.  Role of hormones and neurosteroids in epileptogenesis.

Authors:  Doodipala Samba Reddy
Journal:  Front Cell Neurosci       Date:  2013-07-31       Impact factor: 5.505

  9 in total

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