Literature DB >> 95208

Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells.

B R Williams, R R Golgher, R E Brown, C S Gilbert, I M Kerr.   

Abstract

Until now the interferon-mediated 2'-5' adenine oligonucleotide inhibitors (2-5A) of cell-free protein synthesis have not been detected in intact cells. Here we report their natural occurrence in interferon-treated, EMC virus-infected mouse L cells in amounts consistent with the idea that they play a part in the inhibition of virus growth.

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Year:  1979        PMID： 95208     DOI： 10.1038/282582a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  48 in total

1.  Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.

Authors:  Helle Kristiansen; Christina A Scherer; Maralee McVean; Shawn P Iadonato; Susanne Vends; Karthiga Thavachelvam; Thomas B Steffensen; Kristy A Horan; Thomas Kuri; Friedemann Weber; Søren R Paludan; Rune Hartmann
Journal:  J Virol       Date:  2010-09-15       Impact factor: 5.103

Review 2.  A scientific journey through the 2-5A/RNase L system.

Authors:  Robert H Silverman
Journal:  Cytokine Growth Factor Rev       Date:  2007-07-27       Impact factor: 7.638

Review 3.  Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response.

Authors:  Robert H Silverman
Journal:  J Virol       Date:  2007-09-05       Impact factor: 5.103

4.  Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L.

Authors:  A Zhou; J Paranjape; T L Brown; H Nie; S Naik; B Dong; A Chang; B Trapp; R Fairchild; C Colmenares; R H Silverman
Journal:  EMBO J       Date:  1997-11-03       Impact factor: 11.598

5.  Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells.

Authors:  A P Rice; R Duncan; J W Hershey; I M Kerr
Journal:  J Virol       Date:  1985-06       Impact factor: 5.103

6.  Inhibition of viral mRNA translation in interferon-treated L cells infected with reovirus.

Authors:  A De Benedetti; G J Williams; L Comeau; C Baglioni
Journal:  J Virol       Date:  1985-09       Impact factor: 5.103

7.  2-5A accumulates to high levels in interferon-treated, vaccinia virus-infected cells in the absence of any inhibition of virus replication.

Authors:  A P Rice; W K Roberts; I M Kerr
Journal:  J Virol       Date:  1984-04       Impact factor: 5.103

8.  Cyclic AMP-dependent regulation of activities of synthetase and phosphodiesterase of 2',5'-oligoadenylate in NIH 3T3 cells.

Authors:  A V Itkes; K T Turpaev; O N Kartasheva; C A Kafiani; E S Severin
Journal:  Mol Cell Biochem       Date:  1984       Impact factor: 3.396

9.  Characterization of rat c-myc and adjacent regions.

Authors:  K Hayashi; R Makino; H Kawamura; A Arisawa; K Yoneda
Journal:  Nucleic Acids Res       Date:  1987-08-25       Impact factor: 16.971

10.  Maintenance of protein synthesis in spite of mRNA breakdown in interferon-treated HeLa cells infected with reovirus.

Authors:  T W Nilsen; P A Maroney; C Baglioni
Journal:  Mol Cell Biol       Date:  1983-01       Impact factor: 4.272
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