Variant euchromatic band within 16q12.1.

The enlarged short arm of chromosome 16 resulting in an additional euchromatic band has been regarded as a variant. We present an unreported case with an unusual variant of chromosome 16, where the mother and daughter both have an additional band (q12.1) in the long arm. Its origin is chromosome 16, as revealed by FISH-technique, and its familial nature suggests that it has no clinical significance.