| Literature DB >> 9519293 |
Abstract
Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.Mesh:
Substances:
Year: 1998 PMID: 9519293 DOI: 10.1016/s0959-440x(98)80006-7
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN: 0959-440X Impact factor: 6.809