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Literature DB >> 9516075

The insulin-like growth factors and breast cancer--revisited.

Abstract

In 1992, a special issue of Breast Cancer Research and Treatment was devoted to the insulin-like growth factors and breast cancer. In that issue, identification of the key components of the IGF system was reviewed and their potential role in breast cancer growth was described. In this issue, we revisit the IGF system with particular attention to data that further supports their role in the growth regulation of breast cancer. Several new facets of the IGF system are described, and several laboratories have more clearly defined how each individual component of the IGF system may influence breast cancer biology.

Entities: Disease

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Year: 1998 PMID： 9516075 DOI： 10.1023/a:1005938615798

Source DB: PubMed Journal: Breast Cancer Res Treat ISSN： 0167-6806 Impact factor: 4.872

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Cited

11 in total

1. Transgenic insulin-like growth factor-1 stimulates activation of COX-2 signaling in mammary glands.

Authors: Jie Tian; Isabel Lambertz; Thomas R Berton; Joyce E Rundhaug; Kaoru Kiguchi; Stephanie H Shirley; John Digiovanni; Claudio J Conti; Susan M Fischer; Robin Fuchs-Young
Journal: Mol Carcinog Date: 2011-10-17 Impact factor: 4.784

2. Overexpression of insulin-like growth factor II (IGFII) in ZR-75-1 human breast cancer cells: higher threshold levels of receptor (IGFIR) are required for a proliferative response than for effects on specific gene expression.

Authors: K Abdul-Wahab; D Corcoran; A Perachiotti; P D Darbre
Journal: Cell Prolif Date: 1999-10 Impact factor: 6.831

3. Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice.

Authors: Jie Tian; Thomas R Berton; Stephanie H Shirley; Isabel Lambertz; Irma B Gimenez-Conti; John DiGiovanni; Kenneth S Korach; Claudio J Conti; Robin Fuchs-Young
Journal: J Clin Invest Date: 2011-12-19 Impact factor: 14.808

4. Serum insulin-like growth factor 1 correlates with the risk of nodal metastasis in endocrine-positive breast cancer.

Authors: F Morgillo; F De Vita; G Antoniol; M Orditura; P P Auriemma; M R Diadema; E Lieto; B Savastano; L Festino; M M Laterza; A Fabozzi; J Ventriglia; A Petrillo; F Ciardiello; A Barbarisi; F Iovino
Journal: Curr Oncol Date: 2013-08 Impact factor: 3.677

The insulin-like growth factors and breast cancer--revisited.

1. Transgenic insulin-like growth factor-1 stimulates activation of COX-2 signaling in mammary glands.

2. Overexpression of insulin-like growth factor II (IGFII) in ZR-75-1 human breast cancer cells: higher threshold levels of receptor (IGFIR) are required for a proliferative response than for effects on specific gene expression.

3. Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice.

4. Serum insulin-like growth factor 1 correlates with the risk of nodal metastasis in endocrine-positive breast cancer.

Review 5. Adult growth hormone deficiency in patients with fibromyalgia.

6. Insulin-like growth factor system gene expression in women with type 2 diabetes and breast cancer.

7. The association of breast mitogens with mammographic densities.

Review 8. Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer.

9. Bombesin antagonists inhibit proangiogenic factors in human experimental breast cancers.

10. Biomarkers of the metabolic syndrome and breast cancer prognosis.