Literature DB >> 9515797

A distinct region of chromosome 19p13.3 associated with the sporadic form of adenoma malignum of the uterine cervix.

J Y Lee1, S M Dong, H S Kim, S Y Kim, E Y Na, M S Shin, S H Lee, W S Park, K M Kim, Y S Lee, J J Jang, N J Yoo.   

Abstract

Adenoma malignum (AM) is known to be one of the malignant tumors that is commonly associated with Peutz-Jeghers syndrome. Recently, the genetic locus of Peutz-Jeghers syndrome was mapped to the telomeric region of chromosome 19p. We analyzed nine sporadic cases of AM with high-density loss of heterozygosity to study the region of chromosome 19p13.2-13.3 using eight microsatellite markers. Our deletion mapping data revealed a distinct region with 100% loss of heterozygosity frequency at marker D19S216. This result indicates that a putative tumor suppressor gene for AM is located at D19S216 on chromosomal band 19p13.3 and plays an important role in AM tumorigenesis.

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Mesh：

Year:  1998        PMID： 9515797

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  12 in total

1.  Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome.

Authors:  D C Connolly; H Katabuchi; W A Cliby; K R Cho
Journal:  Am J Pathol       Date:  2000-01       Impact factor: 4.307

2.  Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma.

Authors:  E C Pirog; B Kleter; S Olgac; P Bobkiewicz; J Lindeman; W G Quint; R M Richart; C Isacson
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

3.  LKB1 somatic mutations in sporadic tumors.

Authors:  E Avizienyte; A Loukola; S Roth; A Hemminki; M Tarkkanen; R Salovaara; J Arola; R Bützow; K Husgafvel-Pursiainen; A Kokkola; H Järvinen; L A Aaltonen
Journal:  Am J Pathol       Date:  1999-03       Impact factor: 4.307

4.  Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.

Authors:  Abhinav Achreja; Tao Yu; Anjali Mittal; Srinadh Choppara; Olamide Animasahun; Minal Nenwani; Fulei Wuchu; Noah Meurs; Aradhana Mohan; Jin Heon Jeon; Itisam Sarangi; Anusha Jayaraman; Sarah Owen; Reva Kulkarni; Michele Cusato; Frank Weinberg; Hye Kyong Kweon; Chitra Subramanian; Max S Wicha; Sofia D Merajver; Sunitha Nagrath; Kathleen R Cho; Analisa DiFeo; Xiongbin Lu; Deepak Nagrath
Journal:  Nat Metab       Date:  2022-09-21

5.  Morphologic Features of Gastric-type Cervical Adenocarcinoma in Small Surgical and Cytology Specimens.

Authors:  Gulisa Turashvili; Elizabeth G Morency; Mihaela Kracun; Deborah F DeLair; Sarah Chiang; Robert A Soslow; Kay J Park; Rajmohan Murali
Journal:  Int J Gynecol Pathol       Date:  2019-05       Impact factor: 2.762

6.  Allelic imbalance regions on chromosomes 8p, 17p and 19p related to metastasis of hepatocellular carcinoma: comparison between matched primary and metastatic lesions in 22 patients by genome-wide microsatellite analysis.

Authors:  Lian-Hai Zhang; Lun-Xiu Qin; Zeng-Chen Ma; Sheng-Long Ye; Yin-Kun Liu; Qing-Hai Ye; Xin Wu; Wei Huang; Zhao-You Tang
Journal:  J Cancer Res Clin Oncol       Date:  2003-05-07       Impact factor: 4.553

7.  Polymorphisms of the apoptosis-associated gene DP1L1 (deleted in polyposis 1-like 1) in colon cancer and inflammatory bowel disease.

Authors:  Axel Wellmann; Franz Fogt; Stephan Hollerbach; Jens Hahne; Kerstin Koenig-Hoffmann; Daniela Smeets; Ulrich Brinkmann
Journal:  J Cancer Res Clin Oncol       Date:  2009-11-19       Impact factor: 4.553

8.  Clonality analysis suggests that STK11 gene mutations are involved in progression of lobular endocervical glandular hyperplasia (LEGH) to minimal deviation adenocarcinoma (MDA).

Authors:  Akiko Takatsu; Tsutomu Miyamoto; Chiho Fuseya; Akihisa Suzuki; Hiroyasu Kashima; Akiko Horiuchi; Keiko Ishii; Tanri Shiozawa
Journal:  Virchows Arch       Date:  2013-05-04       Impact factor: 4.064

9.  RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1.

Authors:  Jolita Hendriksen; Francois Fagotto; Hella van der Velde; Martijn van Schie; Jasprien Noordermeer; Maarten Fornerod
Journal:  J Cell Biol       Date:  2005-11-28       Impact factor: 10.539

Review 10.  Cytomorphology of unusual primary tumors in the Pap test.

Authors:  Walid E Khalbuss; Liron Pantanowitz; Sara E Monaco
Journal:  Cytojournal       Date:  2013-08-30       Impact factor: 2.091
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