| Literature DB >> 9514756 |
C López-estraño1, J B Schvartzman, D B Krimer, P Hernández.
Abstract
We investigated the replication of the region where transcription terminates in mouse rDNA. It contains a replication fork barrier (RFB) that behaves in a polar manner, arresting only replication forks moving in the direction opposite to transcription. This RFB consists of several closely spaced fork arrest sites that co-localize with the transcription terminator elements, known as Sal boxes. Sal boxes are the target for mTTF-I (murine transcription termination factor I). These results suggest that both termination of rRNA transcription and replication fork arrest may share cis-acting as well as trans-acting factors. Copyright 1998 Academic Press Limited.Entities:
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Year: 1998 PMID： 9514756 DOI： 10.1006/jmbi.1997.1607
Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469