Left ventricular Doppler diastolic filling patterns in patients with isolated left bundle branch block.

To evaluate the effect of isolated left bundle branch block (LBBB) on diastolic filling patterns, we evaluated 14 subjects with isolated LBBB and 16 age- and sex-matched healthy subjects with normal ventricular conduction by echocardiography. Maximum E-wave velocity, E/A ratio, deceleration time of E wave, and the slope of deceleration of the E wave were lower in subjects with LBBB compared with subjects with normal ventricular conduction. Doppler filling patterns were significantly altered in subjects with isolated LBBB.