Literature DB >> 9513836

A growing demand for Helicobacter pylori culture in the near future?

F Mégraud1.   

Abstract

Culture is the basic method in bacteriology. It allowed the discovery of Helicobacter pylori. Problems in the culture of this fragile, slow-growing bacterium concern transport and processing in the laboratory, but they can be solved. Culture has a 100% specificity. When performed properly, it has a sensitivity in the range of the other best diagnostic methods for Helicobacter pylori. It allows strain typing and, most importantly, susceptibility testing to antibiotics, because an increased rate of acquired resistance of Helicobacter pylori is currently observed. Culture must be performed in clinical trials, at least when antibiotics, to which Helicobacter pylori may be resistant, are used. In clinical practice, culture and susceptibility testing can generally be restricted to treatment failures. However, it is important to monitor Helicobacter pylori susceptibility to antibiotics at a national or regional level in order to give recommendations for primary treatment.

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Year:  1997        PMID: 9513836

Source DB:  PubMed          Journal:  Ital J Gastroenterol Hepatol        ISSN: 1125-8055


  4 in total

1.  Direct detection of Helicobacter pylori resistance to macrolides by a polymerase chain reaction/DNA enzyme immunoassay in gastric biopsy specimens.

Authors:  A Marais; L Monteiro; A Occhialini; M Pina; H Lamouliatte; F Mégraud
Journal:  Gut       Date:  1999-04       Impact factor: 23.059

2.  Virulence genes of Helicobacter pylori in the Dominican Republic.

Authors:  Seiji Shiota; Modesto Cruz; José A Jiménez Abreu; Takahiro Mitsui; Hideo Terao; Mildre Disla; Shun Iwatani; Hiroyuki Nagashima; Miyuki Matsuda; Tomohisa Uchida; Lourdes Tronilo; Eduardo Rodríguez; Yoshio Yamaoka
Journal:  J Med Microbiol       Date:  2014-06-25       Impact factor: 2.472

3.  DPO multiplex PCR as an alternative to culture and susceptibility testing to detect Helicobacter pylori and its resistance to clarithromycin.

Authors:  Philippe Lehours; Elodie Siffré; Francis Mégraud
Journal:  BMC Gastroenterol       Date:  2011-10-17       Impact factor: 3.067

4.  Performance of Routine Helicobacter pylori Invasive Tests in Patients with Dyspepsia.

Authors:  Hsi-Chang Lee; Ting-Chang Huang; Chin-Lin Lin; Kuan-Yang Chen; Chung-Kwe Wang; Deng-Chyang Wu
Journal:  Gastroenterol Res Pract       Date:  2013-12-18       Impact factor: 2.260

  4 in total

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